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- Santos, Tomás; Marinho, H. Susana; Cyrne, Luisa
- Archives of microbiology 2019 v.201 no.1 pp. 123-134
- Saccharomyces cerevisiae; culture media; genes; hydrogen peroxide; myo-inositol; phenotype; phospholipids; plasma membrane; sphingolipids; transporters; yeasts
- ... Myo-inositol is a precursor of several membrane phospholipids and sphingolipids and plays a key role in gene regulation in Saccharomyces cerevisiae (S. cerevisiae). Here, we tested whether H₂O₂ was affecting the levels of the inositol transporters and thus inositol uptake. In S. cerevisiae cells adapted to H₂O₂ Itr1–GFPp accumulated in the plasma membrane until 20 min, concomitantly with an inhibi ...