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You searched for: Author "Wu, Jiaqiang" Remove constraint Author: "Wu, Jiaqiang" Journal Avian diseases Remove constraint Journal: Avian diseases
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1. Efficacy of DNA Vaccines Against Infectious Bursal Disease Virus in Chickens Enhanced by Coadministration with CpG Oligodeoxynucleotide

Author:
Wu, Jiaqiang,   et al.   ; Wang, Xiaoquan; Jiang, Ping; Deen, Shovel; Liu, Xiaowen; Xu, Jiarong;     Show all 6 Authors
Source:
Avian diseases 2003 v.47 no.4 pp. 1305-1312
ISSN:
0005-2086
Subject:
Infectious bursal disease virus; antibodies; atrophy; chickens; cloaca; enzyme-linked immunosorbent assay; fluorescent antibody technique; genes; histopathology; immunization; infectious bursal disease; live vaccines; mortality; oligodeoxyribonucleotides; plasmids; recombinant vaccines; reverse transcriptase polymerase chain reaction; virulence
Abstract:
... The objective of the present study was to investigate the feasibility of a DNA vaccine and CpG oligodeoxynucleotide (ODN) to protect chickens against infectious bursal disease virus (IBDV) infection. Two plasmids DNA carrying VP2 genes of the very virulent (vv) strain of IBDV were constructed with reverse transcription-polymerase chain reaction and designated as pcDNA3.1-VP2 and pCI-VP2. The VP2 p ...
DOI:
10.1637/6045