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- Wu, Jiaqiang, et al. Show all 6 Authors
- Avian diseases 2003 v.47 no.4 pp. 1305-1312
- Infectious bursal disease virus; antibodies; atrophy; chickens; cloaca; enzyme-linked immunosorbent assay; fluorescent antibody technique; genes; histopathology; immunization; infectious bursal disease; live vaccines; mortality; oligodeoxyribonucleotides; plasmids; recombinant vaccines; reverse transcriptase polymerase chain reaction; virulence
- ... The objective of the present study was to investigate the feasibility of a DNA vaccine and CpG oligodeoxynucleotide (ODN) to protect chickens against infectious bursal disease virus (IBDV) infection. Two plasmids DNA carrying VP2 genes of the very virulent (vv) strain of IBDV were constructed with reverse transcription-polymerase chain reaction and designated as pcDNA3.1-VP2 and pCI-VP2. The VP2 p ...