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1. Chicken endothelial cells are highly responsive to viral innate immune stimuli and are susceptible to infections with various avian pathogens

Author:
Lion, Adrien; Esnault, Evelyne; Kut, Emmanuel; Guillory, Vanaïque; Trapp-Fragnet, Laetitia; Soubies, Sébastien M.; Chanteloup, Nathalie; Niepceron, Alisson; Guabiraba, Rodrigo; Marc, Daniel; Eterradossi, Nicolas; Trapp, Sascha; Quéré, Pascale
Source:
Avian pathology 2019 v.48 no.2 pp. 121-134
ISSN:
1465-3338
Subject:
Eimeria tenella; Escherichia coli; Infectious bursal disease virus; Mardivirus; Protozoa; Toll-like receptor 3; agonists; bird diseases; chickens; cytokines; disease susceptibility; embryo (animal); endothelial cells; endothelium; host-pathogen relationships; immunoblotting; infectious diseases; innate immunity; interferon-alpha; interferon-gamma; mammals; models; pathogen-associated molecular patterns; pathogenesis; pathogens; quantitative polymerase chain reaction
Abstract:
... It is well established that the endothelium plays a prominent role in the pathogenesis of various infectious diseases in mammals. However, little is known about the role of endothelial cells (EC) as targets for avian pathogens and their contribution to the pathogenesis of infectious diseases in galliform birds. First, we explored the innate immune response of primary chicken aortic endothelial cel ...
DOI:
10.1080/03079457.2018.1556386