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- Holowka, David, et al. Show all 4 Authors
- BBA - Molecular and Cell Biology of Lipids 2014 v.1841 pp. 1210-1216
- calcium; calcium channels; carbon; crosslinking; electrostatic interactions; energy transfer; exocytosis; linoleic acid; mast cells; oligomerization; plasma membrane; polyunsaturated fatty acids; stearic acid
- ... Polyunsaturated fatty acids (PUFAs) have been found to be effective inhibitors of cell signaling in numerous contexts, and we find that acute addition of micromolar PUFAs such as linoleic acid effectively inhibit of Ca2+ responses in mast cells stimulated by antigen-mediated crosslinking of FcεRI or by the SERCA pump inhibitor, thapsigargin. In contrast, the saturated fatty acid, stearic acid, wit ...
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