PubAg

Main content area

You searched for: Journal BMC complementary and alternative medicine Remove constraint Journal: BMC complementary and alternative medicine Publication Year 2018 Remove constraint Publication Year: 2018 Source 2018 v.18 no.1 Remove constraint Source: 2018 v.18 no.1
Start Over

Search

344  Search Results

« Previous | 1 - 20 of 344 |
Number of results to display per page

Search Results

1. Acacia hydaspica R. Parker ameliorates cisplatin induced oxidative stress, DNA damage and morphological alterations in rat pulmonary tissue

Author:
Afsar, Tayyaba; Razak, Suhail; Almajwal, Ali; Khan, Muhammad Rashid
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 49
ISSN:
1472-6882
Subject:
Acacia; DNA damage; DNA fragmentation; adjuvants; alternative medicine; antioxidant activity; blood vessels; cisplatin; enzymes; ethyl acetate; genotoxicity; histology; histopathology; humans; hydrogen peroxide; lungs; medicinal properties; nitric oxide; oxidative stress; platinum; polyphenols; protective effect; rats; shrubs; silymarin; tissue weight
Abstract:
... BACKGROUND: Cisplatin (CP) drug is platinum compounds used for the treatment of various human malignancies. However, adverse outcomes related to CP restrict its usage. Acacia hydaspica is a natural shrub with various pharmacological properties. The current investigation aimed to assess the protective potential of A. hydaspica polyphenol rich ethyl acetate extract (AHE) against cisplatin (CP) induc ...
DOI:
10.1186/s12906-018-2113-0
PubMed:
29394892
PubMed Central:
PMC5797377

2. Acanthus ebracteatus leaf extract provides neuronal cell protection against oxidative stress injury induced by glutamate

Author:
Prasansuklab, Anchalee; Tencomnao, Tewin
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 278
ISSN:
1472-6882
Subject:
Acanthus; alternative medicine; antioxidant activity; apoptosis; cell viability; gene expression; genes; glutathione; ingredients; leaf extracts; longevity; messenger RNA; mice; models; neurodegenerative diseases; neurons; neuroprotective effect; oxidative toxicity; protein content; reactive oxygen species; traditional medicine; Asia
Abstract:
... BACKGROUND: Acanthus ebracteatus (AE), an herb native to Asia, has been recognized in traditional folk medicine not only for its antioxidant properties and various pharmacological activities but also as an ingredient of longevity formulas. However, its anti-neurodegenerative potential is not yet clearly known. This work aimed to evaluate the protective effect of AE leaf extract against glutamate-i ...
DOI:
10.1186/s12906-018-2340-4

3. 4-Acetylantroquinonol B inhibits lipopolysaccharide-induced cytokine release and alleviates sepsis through of MAPK and NFκB suppression

Author:
Chang, Chien-Hsin; Hsu, Chun-Chieh; Lee, An-Sheng; Wang, Shih-Wei; Lin, Kung-Tin; Chang, Wei-Luen; Peng, Hui-Chin; Huang, Wen-Chiung; Chung, Ching-Hu
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 108
ISSN:
1472-6882
Subject:
Taiwanofungus camphoratus; alternative medicine; anti-inflammatory activity; cell growth; enzyme-linked immunosorbent assay; interleukin-6; lipopolysaccharides; macrophages; medicinal fungi; mice; mitogen-activated protein kinase; mitogen-activated protein kinase kinase; mycelium; neoplasms; phosphorylation; sepsis (infection); transcription factor NF-kappa B; tumor necrosis factor-alpha; Taiwan
Abstract:
... BACKGROUND: Antrodia cinnamomea is an indigenous medicinal mushroom in Taiwan, commonly used for the treatment of cancers and inflammatory disorders. 4-acetylantroquinonol B (4AAQB) is one of the active component isolated from the mycelium of A. cinnamomea. However, whether 4AAQB exhibits anti-inflammatory effect is not clear. METHODS: The anti-inflammatory activity of 4AAQB was examined by ELISA ...
DOI:
10.1186/s12906-018-2172-2
PubMed:
29566694
PubMed Central:
PMC5865343

4. A Chinese herbal decoction, Jian-Pi-Yi-Shen, regulates the expressions of erythropoietin and pro-inflammatory cytokines in cultured cells

Author:
Chen, Jianping; Gong, Amy G. W.; Liu, Xiaoyan; Li, Zhonggui; Qi, Airong; Dong, Tina T. X.; Yi, Tiegang; Tsim, Karl W. K.; Li, Shunmin
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 119
ISSN:
1472-6882
Subject:
RNA; alternative medicine; anemia; cultured cells; dose response; erythropoietin; genes; hypoxia; immune response; interleukin-1beta; interleukin-6; kidney diseases; luciferase; macrophages; patients; quantitative polymerase chain reaction; tumor necrosis factor-alpha
Abstract:
... BACKGROUND: A Chinese herbal formula, namely Jian-Pi-Yi-Shen (JPYS), has been clinically prescribed for patients with chronic kidney disease associated-anemia, and which can improve the patient’s immunological system. However, the mechanisms of JPYS involved in anemia and immune response have not been investigated. To study the role of JPYS in regulating hematopoietic and immunological functions, ...
DOI:
10.1186/s12906-018-2146-4
PubMed:
29615029
PubMed Central:
PMC5883303

5. Acid-base fractions separated from Streblus asper leaf ethanolic extract exhibited antibacterial, antioxidant, anti-acetylcholinesterase, and neuroprotective activities

Author:
Prasansuklab, Anchalee; Theerasri, Atsadang; Payne, Matthew; Ung, Alison T.; Tencomnao, Tewin
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 223
ISSN:
1472-6882
Subject:
2,2-diphenyl-1-picrylhydrazyl; Alzheimer disease; Gram-positive bacteria; Streblus asper; acetylcholinesterase; alternative medicine; antibacterial properties; antioxidant activity; antioxidants; cell lines; cell viability; chemical composition; chemical constituents of plants; ethanol; fatty acids; gas chromatography-mass spectrometry; leaf extracts; leaves; minimum inhibitory concentration; neurons; neuroprotective effect; plant hormones; steroids; terpenoids; thin layer chromatography; toxicity; South East Asia
Abstract:
... BACKGROUND: Streblus asper is a well-known plant native to Southeast Asia. Different parts of the plant have been traditionally used for various medicinal purposes. However, there is very little scientific evidence reporting its therapeutic benefits for potential treatment of Alzheimer’s disease (AD). The study aimed to evaluate antibacterial, antioxidant, acetylcholinesterase (AChE) inhibition, a ...
DOI:
10.1186/s12906-018-2288-4
PubMed:
30041641
PubMed Central:
PMC6057052

6. A comparative study of three conservative treatments in patients with lumbar spinal stenosis: lumbar spinal stenosis with acupuncture and physical therapy study (LAP study)

Author:
Oka, Hiroyuki; Matsudaira, Ko; Takano, Yuichi; Kasuya, Daichi; Niiya, Masaki; Tonosu, Juichi; Fukushima, Masayoshi; Oshima, Yasushi; Fujii, Tomoko; Tanaka, Sakae; Inanami, Hirohiko
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 19
ISSN:
1472-6882
Subject:
acetaminophen; acupuncture; clinical trials; decision making; drug therapy; exercise; hospitals; lumbar spine; patients; physical therapy; questionnaires; spinal stenosis; surgery
Abstract:
... BACKGROUND: Although the efficiency of conservative management for lumbar spinal stenosis (LSS) has been examined, different conservative management approaches have not been compared. We have performed the first comparative trial of three types of conservative management (medication with acetaminophen, exercise, and acupuncture) in Japanese patients with LSS. METHODS: Patients with L5 root radicul ...
DOI:
10.1186/s12906-018-2087-y
PubMed:
29351748
PubMed Central:
PMC5775532

7. A comprehensive study of the potential phytomedicinal use and toxicity of invasive Tithonia species in South Africa

Author:
Omokhua, Aitebiremen Gift; Abdalla, Muna Ali; Van Staden, Johannes; McGaw, Lyndy Joy
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 272
ISSN:
1472-6882
Subject:
Ames test; Mycobacterium; Tithonia diversifolia; alternative medicine; anti-infective agents; antimicrobial properties; bioactive compounds; colorimetry; cytotoxicity; flavonoids; fungi; genotoxicity; leaf extracts; medicinal properties; minimum inhibitory concentration; mutagens; secondary infection; tannins; virulent strains; Asia; Central America; Mexico; South Africa; Venezuela
Abstract:
... BACKGROUND: Tithonia diversifolia and T. rotundifolia belong to the Asteraceae family and are native to Mexico and Central America. These plants have become invasive in parts of tropical Africa and Asia where they have become an ecological, agricultural and economic burden. Tithonia diversifolia is exploited by locals in its native and most parts of its invasive range as a source of medicines; how ...
DOI:
10.1186/s12906-018-2336-0

8. Acupuncture decreased the risk of coronary heart disease in patients with rheumatoid arthritis in Taiwan: a Nationwide propensity score-matched study

Author:
Wu, Mei-Yao; Huang, Ming-Cheng; Liao, Hou-Hsun; Chiang, Jen-Huai; Lee, Yu-Chen; Hsu, Chung-Y; Sun, Mao-Feng; Yen, Hung-Rong
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 341
ISSN:
1472-6882
Subject:
Oriental traditional medicine; acupuncture; comorbidity; coronary disease; databases; diabetes mellitus; health insurance; hyperlipidemia; hypertension; patients; rheumatoid arthritis; risk; Taiwan
Abstract:
... BACKGROUND: Patients with rheumatoid arthritis (RA) have a higher risk of coronary heart disease (CHD). Acupuncture, a commonly used treatment for patients with RA, has not been reported to prevent CHD in patients with RA. We aimed to assess the risk of developing CHD in acupuncture users and non-users of patients with RA. METHODS: We identified 29,741 patients with newly diagnosed RA from January ...
DOI:
10.1186/s12906-018-2384-5

9. Acute and chronic toxicity of a polyherbal preparation – Jueyin granules

Author:
Chen, Yu; Guo, Dong-jie; Deng, Hui; Wu, Min-feng; Zhang, Ya-Nan; Li, Su; Xu, Rong; Chen, Jie; Jin, Xing-xiu; Li, Bin; Xu, Qi; Li, Fu-lun
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 148
ISSN:
1472-6882
Subject:
acute toxicity; alternative medicine; animal models; biomedical research; body weight; chronic toxicity; females; granules; hematologic tests; herbal medicines; histopathology; humans; laboratory animals; males; mice; mortality; psoriasis; rats; toxicity testing
Abstract:
... BACKGROUND: The potential toxicity of Chinese herbal medicine has attracted more attention in recent years. Jueyin granules (JYG), a polyherbal formula, have been proven to be an effective agent for treating psoriasis in both animal models and clinical research. However, little is known about the possible acute and chronic toxicity of JYG. The objective of this study was to investigate the safety ...
DOI:
10.1186/s12906-018-2211-z
PubMed:
29739373
PubMed Central:
PMC5941322

10. Acute and sub-acute oral toxicity of Dracaena cinnabari resin methanol extract in rats

Author:
Al-Afifi, Nashwan Abdullah; Alabsi, Aied Mohammed; Bakri, Marina Mohd; Ramanathan, Anand
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 50
ISSN:
1472-6882
Subject:
Dracaena; acute toxicity; alternative medicine; blood; coasts; death; dietary exposure; females; guidelines; heart; hematologic tests; histopathology; kidneys; liver; lungs; males; methanol; oral administration; rats; spleen; tissue weight; toxicity testing; trees; Yemen
Abstract:
... BACKGROUND: Dracaena cinnabari (DC) is a perennial tree that located on the Southern coast of Yemen native to the Socotra Island. This tree produces a deep red resin known as the Dragon’s blood, the Twobrother’s Blood or Damm Alakhwain. The current study performed to evaluate the safety of the DC resin methanol extract after a single or 28 consecutive daily oral administrations. METHODS: In assess ...
DOI:
10.1186/s12906-018-2110-3
PubMed:
29402248
PubMed Central:
PMC5800047

11. Acute effect of Clitoria ternatea flower beverage on glycemic response and antioxidant capacity in healthy subjects: a randomized crossover trial

Author:
Chusak, Charoonsri; Thilavech, Thavaree; Henry, Christiani Jeyakumar; Adisakwattana, Sirichai
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 6
ISSN:
1472-6882
Subject:
Clitoria ternatea; alternative medicine; anthocyanins; beverages; blood glucose; body mass index; clinical trials; cross-over studies; flowers; glucose; glycemic effect; hypoglycemia; ingestion; insulin; lipid peroxidation; malondialdehyde; men; oxygen radical absorbance capacity; sucrose; thiols; uric acid
Abstract:
... BACKGROUND: Clitoria ternatea L., a natural food-colorant containing anthocyanin, demonstrated antioxidant and antihyperglycemic activity. The aim of this study was to determine the effects of Clitoria ternatea flower extract (CTE) on postprandial plasma glycemia response and antioxidant status in healthy men. METHODS: In a randomized, crossover study, 15 healthy men (ages 22.53 ± 0.30 years; with ...
DOI:
10.1186/s12906-017-2075-7
PubMed:
29310631
PubMed Central:
PMC5759795

12. Adenosine and adenosine-5′-monophosphate ingestion ameliorates abnormal glucose metabolism in mice fed a high-fat diet

Author:
Ardiansyah,; Inagawa, Yuto; Koseki, Takuya; Agista, Afifah Zahra; Ikeda, Ikuo; Goto, Tomoko; Komai, Michio; Shirakawa, Hitoshi
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 304
ISSN:
1472-6882
Subject:
AMP-activated protein kinase; adenosine; adenosine monophosphate; alternative medicine; animal disease models; blood serum; diabetes; genes; glucose; glucose tolerance tests; high fat diet; hypertension; ingestion; insulin resistance; insulin tolerance test; lipid peroxidation; messenger RNA; mice; muscles; obesity; phosphorylation; protein synthesis; skeletal muscle
Abstract:
... BACKGROUND: We have previously reported that ingestion of adenosine (ADN) and adenosine-5′-monophosphate (AMP) improves abnormal glucose metabolism in the stroke-prone spontaneously hypertensive rat model of non-obesity-associated insulin resistance. In this study, we investigated the effect of ADN and AMP ingestion on glucose metabolism in mice with high-fat diet-induced obesity. METHODS: Seven-w ...
DOI:
10.1186/s12906-018-2367-6

13. A dual continuum model of the reasons for use of complementary health approaches among overweight and obese adults: findings from the 2012 NHIS

Author:
Upchurch, Dawn M.; Liang, Linghui; Sirois, Fuschia M.
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 339
ISSN:
1472-6882
Subject:
adults; alternative medicine; body mass index; burden of disease; models; motivation; overweight; people; regression analysis; risk; surveys; United States
Abstract:
... BACKGROUND: Obese and overweight individuals have greater illness and disease burden, but previous findings from the 2002 National Health Interview Survey (NHIS) suggest that they are no more likely to use complementary health approaches (CHA) than those of normal weight. The current study investigates the relationship between weight status and CHA use, and among CHA users, examines differences in ...
DOI:
10.1186/s12906-018-2404-5

14. A Lanosteryl triterpene from Protorhus longifolia augments insulin signaling in type 1 diabetic rats [Erratum: Dec. 2018, v. 18(1), p.318]

Author:
Mabhida, Sihle Ephraim; Johnson, Rabia; Ndlovu, Musawenkosi; Sangweni, Nonhlakanipho Felicia; Louw, Johan; Opoku, Andrew; Mosa, Rebamang Anthony
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 265
ISSN:
1472-6882
Subject:
alternative medicine; animal disease models; antioxidants; bark; blood glucose; blood serum; c-peptide; catalase; diabetes; glutathione; glycemic effect; histology; inflammation; insulin resistance; interleukin-6; islets of Langerhans; malondialdehyde; muscles; oral administration; oxidative stress; protein synthesis; rats; skeletal muscle; superoxide dismutase; triterpenoids
Abstract:
... BACKGROUND: A substantial literature supports antidiabetic properties of the lanosteryl triterpene (methyl-3β-hydroxylanosta-9,24-dien-21-oate, RA-3) isolated from Protorhus longifolia stem bark. However, the molecular mechanism(s) associated with the antihyperglycemic properties of the triterpene remained to be explored. The current study aimed at investigating the molecular mechanism(s) through ...
DOI:
10.1186/s12906-018-2337-z

15. Aloe-emodin induces apoptosis in human oral squamous cell carcinoma SCC15 cells

Author:
Li, Qihong; Wen, Jun; Yu, Kaitao; Shu, Yao; He, Wulin; Chu, Hongxing; Zhang, Bin; Ge, Cheng
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 296
ISSN:
1472-6882
Subject:
Rheum undulatum; Western blotting; alternative medicine; anthraquinones; antineoplastic agents; apoptosis; caspase-3; caspase-9; cell proliferation; cell viability; dose response; drug resistance; drug therapy; flow cytometry; humans; ingredients; inhibitory concentration 50; mouth neoplasms; patients; pharmacodynamics; pharyngeal neoplasms; proteins; squamous cell carcinoma; thiazolyl blue
Abstract:
... BACKGROUND: Oral and pharyngeal cancer is the most common malignant human cancers. Chemotherapy is an effective approach for anti-oral cancer therapy, while the drug tolerance and resistance remain a problem for oral cancer patients. Aloe-emodin, rhein and physcion are classified as anthraquinones, which are the main pharmacodynamic ingredients of Rheum undulatum L.. This study was undertaken to i ...
DOI:
10.1186/s12906-018-2353-z

16. Ameliorative effect of taurine-chloramine in azathioprine-induced testicular damage; a deeper insight into the mechanism of protection

Author:
Schaalan, Mona F.; Ramadan, Basma K.; H. Abd Elwahab, Azza
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 255
ISSN:
1472-6882
Subject:
DNA damage; alternative medicine; antineoplastic agents; antioxidants; apoptosis; atrophy; caspase-9; catalase; drug therapy; glutathione; inducible nitric oxide synthase; interleukin-1beta; male fertility; males; oxidative stress; protective effect; protein synthesis; rats; sex hormones; sperm quality; superoxide dismutase; taurine; testes; toxic substances; toxicity; tumor necrosis factor-alpha; viability
Abstract:
... BACKGROUND: The male reproductive system is a sensitive and intricate process that can be distressed following exposure to various toxicants. Therapeutic drugs, especially chemotherapeutics, can also adversely affect male fertility by instigating hormonal changes leading to testicular cells injury. Azathioprine (AZA) is an effective anticancer drug, but some cases of testicular toxicity have been ...
DOI:
10.1186/s12906-018-2272-z

17. Anacardic acid inhibits pancreatic cancer cell growth, and potentiates chemotherapeutic effect by Chmp1A - ATM - p53 signaling pathway

Author:
Park, Maiyon; Upton, Danielle; Blackmon, Melodie; Dixon, Valerie; Craver, Scott; Neal, Dawn; Perkins, Derek
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 71
ISSN:
1472-6882
Subject:
Western blotting; acid treatment; alternative medicine; antineoplastic activity; cell growth; cell lines; cell viability; chromatin; cytotoxicity; death; dose response; drug therapy; fluorouracil; humans; immunocytochemistry; neoplasm cells; pancreatic neoplasms; patients; signal transduction; viability assays
Abstract:
... BACKGROUND: Pancreatic cancer is one of the leading causes of cancer related death and its incidence has risen steadily. Although anticancer drugs have been developed based on the new molecular findings, the drugs have produced unsatisfactory results due to toxicity and resistance. Thus, a complementary therapeutic intervention is urgently needed for pancreatic cancer patients. METHODS: The aim of ...
DOI:
10.1186/s12906-018-2139-3
PubMed:
29463243
PubMed Central:
PMC5819688

18. An assessment of the use of complementary and alternative medicine by Korean people using an adapted version of the standardized international questionnaire (I-CAM-QK): a cross-sectional study of an internet survey

Author:
Lee, Ju Ah; Sasaki, Yui; Arai, Ichiro; Go, Ho-Yeon; Park, Sunju; Yukawa, Keiko; Nam, Yun Kung; Ko, Seong-Gyu; Motoo, Yoshiharu; Tsutani, Kiichiro; Lee, Myeong Soo
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 238
ISSN:
1472-6882
Subject:
Internet; Koreans; acupuncture; cross-sectional studies; dietary supplements; drugs; physicians; questionnaires; surveys; traditional medicine; Korean Peninsula
Abstract:
... BACKGROUND: In Korea, there are two types of medical doctors: one practises conventional medicine (hereafter called a physician), and the other practises traditional medicine (hereafter called a Korean medical doctor). This study aimed to compare the provision of complementary and alternative medicine (CAM) by these providers to CAM use per self-judgement in Korea. METHODS: We analysed 1668 Korean ...
DOI:
10.1186/s12906-018-2294-6
PubMed:
30103722
PubMed Central:
PMC6090824

19. An in vivo immunomodulatory and anti-inflammatory study of fermented Dendropanax morbifera Léveille leaf extract

Author:
Birhanu, Biruk Tesfaye; Kim, Jin-Yoon; Hossain, Md. Akil; Choi, Jae-Won; Lee, Sam-Pin; Park, Seung-Chun
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 222
ISSN:
1472-6882
Subject:
B-lymphocytes; Dendropanax morbifer; T-lymphocytes; alternative medicine; antigens; bioactive properties; concanavalin A; dose response; enzyme-linked immunosorbent assay; females; flow cytometry; immune response; immunoglobulin G; immunomodulators; infectious diseases; interleukin-1alpha; interleukin-1beta; interleukin-4; leaf extracts; lipopolysaccharides; lymphocyte proliferation; medicinal plants; mice; new drugs; phenotype; splenocytes; trees
Abstract:
... BACKGROUND: Medicinal plants represent a source of new drugs for the prevention and treatment of infectious diseases. Dendropanax morbifera Léveille is an economically and medicinally important subtropical tree that has various biological activities. However, its ability to affect immune responses in vivo is unknown. Hence, this study was designed to examine the immunomodulatory activity of fermen ...
DOI:
10.1186/s12906-018-2282-x
PubMed:
30041643
PubMed Central:
PMC6057031

20. Anti-aging potential of extracts from Sclerocarya birrea (A. Rich.) Hochst and its chemical profiling by UPLC-Q-TOF-MS

Author:
Shoko, Tinotenda; Maharaj, Vinesh J.; Naidoo, Dashnie; Tselanyane, Malefa; Nthambeleni, Rudzani; Khorombi, Eric; Apostolides, Zeno
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 54
ISSN:
1472-6882
Subject:
EDTA (chelating agent); Sclerocarya birrea subsp. caffra; acetone; alternative medicine; anti-aging properties; catechin; chromatography; collagen; collagenase; color; computer software; cosmetics; defatting; elastase; elastin; enzyme activity; enzyme inhibition; epicatechin; epigallocatechin gallate; ethanol; ethyl acetate; extracellular matrix; fruits; hexane; ingredients; leaf extracts; leaves; methanol; oils; phytopharmaceuticals; quinic acid; stems
Abstract:
... BACKGROUND: Degradation of components of the extracellular matrix such as elastin and collagen by elastase and collagenase accelerates skin aging. Phytochemicals that inhibit the activity of these enzymes can be developed as anti-aging ingredients. In this study, an investigation of the anti-aging properties of Sclerocarya birrea (A. Rich.) Hochst (Marula) extracts was conducted in vitro with the ...
DOI:
10.1186/s12906-018-2112-1
PubMed:
29415712
PubMed Central:
PMC5804067