U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Journal name BMC genetics Remove constraint Journal name: BMC genetics Publication year rev 7982-2018 Remove constraint Publication year rev: 7982-2018 Source 2018 v.19 no.1 Remove constraint Source: 2018 v.19 no.1
Start Over

Search

94  Search Results

« Previous | 1 - 20 of 94 |
Number of results to display per page

Search Results

1. Analysis of coastal cod (Gadus morhua L.) sampled on spawning sites reveals a genetic gradient throughout Norway’s coastline

Author:
Geir Dahle; María Quintela; Torild Johansen; Jon-Ivar Westgaard; François Besnier; Asgeir Aglen; Knut E. Jørstad; Kevin A. Glover
Source:
BMC genetics 2018 v.19 no.1 pp. 42
ISSN:
1471-2156
Subject:
Gadus morhua; alleles; coasts; data collection; effective population size; fisheries; genetic markers; genetic variation; genomics; genotyping; heterozygosity; introgression; loci; marine fish; microsatellite repeats; otoliths; population genetics; population structure; spawning; Arctic region; Norway
Abstract:
... BACKGROUND: Atlantic cod (Gadus morhua L.) has formed the basis of many economically significant fisheries in the North Atlantic, and is one of the best studied marine fishes, but a legacy of overexploitation has depleted populations and collapsed fisheries in several regions. Previous studies have identified considerable population genetic structure for Atlantic cod. However, within Norway, which ...
DOI:
10.1186/s12863-018-0625-8
PubMed:
29986643
PubMed Central:
PMC6036686

2. Associations of sex hormone-binding globulin and testosterone with genome-wide DNA methylation

Author:
Ryan Arathimos; Gemma C. Sharp; Raquel Granell; Kate Tilling; Caroline L. Relton
Source:
BMC genetics 2018 v.19 no.1 pp. 113
ISSN:
1471-2156
Subject:
DNA methylation; adolescence; childhood; children; epigenetics; females; genes; genomics; heritability; longitudinal studies; males; parents; risk; sex hormone-binding globulin; testosterone
Abstract:
... BACKGROUND: Levels of sex hormone-binding globulin (SHBG) and the androgen testosterone have been associated with risk of diseases throughout the lifecourse. Although both SHBG and testosterone have been shown to be highly heritable, only a fraction of that heritability has been explained by genetic studies. Epigenetic modifications such as DNA methylation may explain some of the missing heritabil ...
DOI:
10.1186/s12863-018-0703-y
PubMed:
30547757
PubMed Central:
PMC6295101

3. Can metamorphosis survival during larval development in spiny lobster Sagmariasus verreauxi be improved through quantitative genetic inheritance?

Author:
Nguyen H. Nguyen; Quinn P. Fitzgibbon; Jane Quinn; Greg Smith; Stephen Battaglene; Wayne Knibb
Source:
BMC genetics 2018 v.19 no.1 pp. 27
ISSN:
1471-2156
Subject:
Sagmariasus verreauxi; analysis of variance; economic valuation; genetic correlation; genetic markers; genetic variance; hatcheries; heritability; inheritance (genetics); instars; larvae; larval development; lobster culture; lobsters; metamorphosis; molting; natural selection; parentage; phenotype; progeny; rearing; sires; statistical models; survival rate
Abstract:
... BACKGROUND: One of the major impediments to spiny lobster aquaculture is the high cost of hatchery production due to the long and complex larval cycle and poor survival during the many moult stages, especially at metamorphosis. We examined if the key trait of larval survival can be improved through selection by determining if genetic variance exists for this trait. Specifically, we report, for the ...
DOI:
10.1186/s12863-018-0621-z
PubMed:
29728054
PubMed Central:
PMC5936031

4. Characterization and functional analyses of the human HTR1A gene: 5’ regulatory region modulates gene expression in vitro

Author:
Xue Wu; Feng-ling Xu; Mei Ding; Jing-jing Zhang; Jun Yao; Bao-jie Wang
Source:
BMC genetics 2018 v.19 no.1 pp. 115
ISSN:
1471-2156
Subject:
cell lines; chemiluminescence; computer software; gene expression; humans; luciferase; neurotransmitters; prediction; protein synthesis; receptors; schizophrenia; serotonin; transcription factors; transcription initiation site
Abstract:
... BACKGROUND: The serotonin neurotransmitter (5-HT) and its receptors have important roles in neuropsychiatric disorders such as schizophrenia. The aim of this study was to investigate the functional sequences of the 5′ regulation region of the human HTR1A gene to explore the effects on the expression of the 5-HT1A receptor. METHODS: Fourteen recombinant pGL3-basic vectors containing deletion fragme ...
DOI:
10.1186/s12863-018-0708-6
PubMed:
30594152
PubMed Central:
PMC6311061

5. Characterization of the late embryogenesis abundant (LEA) proteins family and their role in drought stress tolerance in upland cotton

Author:
Richard Odongo Magwanga; Pu Lu; Joy Nyangasi Kirungu; Hejun Lu; Xingxing Wang; Xiaoyan Cai; Zhongli Zhou; Zhenmei Zhang; Haron Salih; Kunbo Wang; Fang Liu
Source:
BMC genetics 2018 v.19 no.1 pp. 6
ISSN:
1471-2156
Subject:
drought tolerance; phylogeny; drought; hydrophobicity; Gossypium hirsutum; Gossypium tomentosum; hydrophilicity; water stress; gene expression; microRNA; genotype; embryogenesis; introns; crop production; cultivars; freshwater; chromosomes; gene ontology; textile industry; cash crops; cotton; proteins; stress response; gene duplication
Abstract:
... BACKGROUND: Late embryogenesis abundant (LEA) proteins are large groups of hydrophilic proteins with major role in drought and other abiotic stresses tolerance in plants. In-depth study and characterization of LEA protein families have been carried out in other plants, but not in upland cotton. The main aim of this research work was to characterize the late embryogenesis abundant (LEA) protein fam ...
DOI:
10.1186/s12863-017-0596-1
PubMed:
29334890
PubMed Central:
PMC5769447

6. Combining controls can improve power in two-stage association studies

Author:
James Liley
Source:
BMC genetics 2018 v.19 no.1 pp. 89
ISSN:
1471-2156
Subject:
case-control studies; computer software; genetic techniques and protocols; genome-wide association study; genomics; mathematics and statistics
Abstract:
... BACKGROUND: High dimensional case control studies are ubiquitous in the biological sciences, particularly genomics. To maximise power while constraining cost and to minimise type-1 error rates, researchers typically seek to replicate findings in a second experiment on independent cohorts before proceeding with further analyses. This can be an expensive procedure, particularly when control samples ...
DOI:
10.1186/s12863-018-0675-y
PubMed:
30285617
PubMed Central:
PMC6171163

7. Comparative RNA-Seq analysis reveals a critical role for brassinosteroids in rose (Rosa hybrida) petal defense against Botrytis cinerea infection

Author:
Xintong Liu; Xiaoqian Cao; Shaochuan Shi; Na Zhao; Dandan Li; Peihong Fang; Xi Chen; Weicong Qi; Zhao Zhang
Source:
BMC genetics 2018 v.19 no.1 pp. 62
ISSN:
1471-2156
Subject:
Botrytis cinerea; Rosa; biosynthesis; brassinosteroids; corolla; death; disease resistance; gene expression regulation; gene ontology; gene regulatory networks; genes; gray mold; host-pathogen relationships; hybrids; immunologic receptors; ornamental plants; plant hormones; plant pathogenic fungi; secondary metabolites; sequence analysis; signal transduction; transcription (genetics); transcription factors; transcriptome; transcriptomics
Abstract:
... BACKGROUND: One of the most popular ornamental plants worldwide, roses (Rosa sp.), are very susceptible to Botrytis gray mold disease. The necrotrophic infection of rose petals by B. cinerea causes the collapse and death of these tissues in both the growth and post-harvest stages, resulting in serious economic losses. To understand the molecular basis of rose resistance against B. cinerea, we prof ...
DOI:
10.1186/s12863-018-0668-x
PubMed:
30126371
PubMed Central:
PMC6102922

8. Comparing SNP panels and statistical methods for estimating genomic breed composition of individual animals in ten cattle breeds

Author:
Jun He; Yage Guo; Jiaqi Xu; Hao Li; Anna Fuller; Richard G. Tait Jr; Xiao-Lin Wu; Stewart Bauck
Source:
BMC genetics 2018 v.19 no.1 pp. 56
ISSN:
1471-2156
Subject:
DNA shuffling; Santa Gertrudis; breeding value; cattle; cost effectiveness; crossbreds; crossing; dairy breeds; gene frequency; genomics; genotype; prediction; regression analysis; single nucleotide polymorphism; statistical models
Abstract:
... BACKGROUND: SNPs are informative to estimate genomic breed composition (GBC) of individual animals, but selected SNPs for this purpose were not made available in the commercial bovine SNP chips prior to the present study. The primary objective of the present study was to select five common SNP panels for estimating GBC of individual animals initially involving 10 cattle breeds (two dairy breeds an ...
DOI:
10.1186/s12863-018-0654-3
PubMed:
30092776
PubMed Central:
PMC6085684

9. Correction to: Application of geographic population structure (GPS) algorithm for biogeographical analyses of populations with complex ancestries: a case study of South Asians from 1000 genomes project

Author:
Ranajit Das; Priyanka Upadhyai
Source:
BMC genetics 2018 v.19 no.1 pp. 96
ISSN:
1471-2156
Subject:
Asians; algorithms; biogeography; case studies; genome; population structure
Abstract:
... Following publication of the original article [1], the authors flagged that acknowledgment of their equal contribution is omitted in the article [1]. ...
DOI:
10.1186/s12863-018-0683-y
PubMed:
30359224
PubMed Central:
PMC6201577

10. Correction to: Landraces of snake melon, an ancient Middle Eastern crop, reveal extensive morphological and DNA diversity for potential genetic improvement

Author:
Samer Omari; Yuri Kamenir; Jennifer I. C. Benichou; Sarah Pariente; Hanan Sela; Rafael Perl-Treves
Source:
BMC genetics 2018 v.19 no.1 pp. 44
ISSN:
1471-2156
Subject:
Cucumis melo subsp. melo var. flexuosus; DNA; genetic improvement; landraces
Abstract:
... Following publication of the original article [1], the authors reported the need for a more detailed acknowledgement of the source of the samples that were analyzed and their coordinates, which are discussed in the ‘Methods’ section of the article. This Correction provides an addition to the ‘Methods’ section, and a subsequently revised ‘Acknowledgements’ and ‘Availability of data and materials’ s ...
DOI:
10.1186/s12863-018-0632-9
PubMed:
30001200
PubMed Central:
PMC6042412

11. Development of SNP assays for hessian fly response genes, Hfr-1 and Hfr-2, for marker-assisted selection in wheat breeding

Author:
Mui-Keng Tan; Mustapha El-Bouhssini; Ossie Wildman; Wuletaw Tadesse; Grant Chambers; Shuming Luo; Livinus Emebiri
Source:
BMC genetics 2018 v.19 no.1 pp. 50
ISSN:
1471-2156
Subject:
Mayetiola destructor; alleles; breeding programs; chromosomes; cultivars; exons; genotype; genotyping; germplasm; isoleucine; lectins; marker-assisted selection; single nucleotide polymorphism; valine; wheat
Abstract:
... BACKGROUND: The Hessian fly response genes, Hfr-1 and Hfr-2, have been reported to be significantly induced in a Hessian fly attack. Nothing is known about the allelic variants of these two genes in susceptible (S) and resistant (R) wheat cultivars. RESULTS: Basic local alignment search tool (BLAST) analysis of Hessian fly response genes have identified three alleles of Hessian fly response gene 1 ...
DOI:
10.1186/s12863-018-0659-y
PubMed:
30064355
PubMed Central:
PMC6066933

12. Diversity of plant defense elicitor peptides within the Rosaceae

Author:
Cristina Ruiz; Anna Nadal; Laura Foix; Laura Montesinos; Emilio Montesinos; Maria Pla
Source:
BMC genetics 2018 v.19 no.1 pp. 11
ISSN:
1471-2156
Subject:
Crataegus; Malus; Photinia; Prunus; Pyracantha coccinea; Pyrus; Xanthomonas arboricola pv. pruni; apples; bacteria; consensus sequence; cultivars; disease resistance; edible species; elicitors; fungi; gene expression; genes; herbivores; immunity; models; peaches; pears; peptides; phylogeny; plant pathogens; receptors
Abstract:
... BACKGROUND: Plant elicitor peptides (Peps) are endogenous molecules that induce and amplify the first line of inducible plant defense, known as pattern-triggered immunity, contributing to protect plants against attack by bacteria, fungi and herbivores. Pep topic application and transgenic expression have been found to enhance disease resistance in a small number of model plant-pathogen systems. Th ...
DOI:
10.1186/s12863-017-0593-4
PubMed:
29361905
PubMed Central:
PMC5782389

13. Exome sequencing identifies gene variants and networks associated with extreme respiratory outcomes following preterm birth

Author:
Aaron Hamvas; Rui Feng; Yingtao Bi; Fan Wang; Soumyaroop Bhattacharya; Jared Mereness; Madhurima Kaushal; C Michael Cotten; Philip L Ballard; Thomas J Mariani; PROP Investigators
Source:
BMC genetics 2018 v.19 no.1 pp. 94
ISSN:
1471-2156
Subject:
bronchopulmonary dysplasia; cAMP-dependent protein kinase; epidermal growth factor receptors; gene expression; gene regulatory networks; genes; genetic variation; infant diseases; loci; mitogen-activated protein kinase; morbidity; phenotype; premature birth; risk; sequence analysis
Abstract:
... BACKGROUND: Previous studies have identified genetic variants associated with bronchopulmonary dysplasia (BPD) in extremely preterm infants. However, findings with genome-wide significance have been rare, and not replicated. We hypothesized that whole exome sequencing (WES) of premature subjects with extremely divergent phenotypic outcomes could facilitate the identification of genetic variants or ...
DOI:
10.1186/s12863-018-0679-7
PubMed:
30342483
PubMed Central:
PMC6195962

14. Extent of third-order linkage disequilibrium in a composite line of Iberian pigs

Author:
Luis Gomez-Raya; Luis Silio; Wendy M. Rauw; Luis Alberto Gracia-Cortés; Carmen Rodríguez
Source:
BMC genetics 2018 v.19 no.1 pp. 60
ISSN:
1471-2156
Subject:
Iberian (swine breed); algorithms; computers; gene frequency; genetic drift; genome-wide association study; linkage disequilibrium; loci; models; single nucleotide polymorphism; sows
Abstract:
... BACKGROUND: Previous studies on linkage disequilibrium have investigated second order linkage disequilibrium in animal and plant populations. The objective of this paper was to investigate the genome-wide levels of third order linkage disequilibrium in a composite line founded by admixture of four Iberian pig strains. A model for the generation of third order linkage disequilibrium by population a ...
DOI:
10.1186/s12863-018-0661-4
PubMed:
30119622
PubMed Central:
PMC6098602

15. Genetic characterization of inbred lines from Shaan A and B groups for identifying loci associated with maize grain yield

Author:
Ting Li; Jianzhou Qu; Yahui Wang; Liguo Chang; Kunhui He; Dongwei Guo; Xinghua Zhang; Shutu Xu; Jiquan Xue
Source:
BMC genetics 2018 v.19 no.1 pp. 63
ISSN:
1471-2156
Subject:
Zea mays; chromosome mapping; corn; gene frequency; genes; genetic improvement; genetic variation; genotyping by sequencing; grain yield; hybrids; inbred lines; kinship; loci; pedigree; plant breeding; population structure; single nucleotide polymorphism
Abstract:
... BACKGROUND: Increasing grain yield is a primary objective of maize breeding. Dissecting the genetic architecture of grain yield furthers genetic improvements to increase yield. Presented here is an association panel composed of 126 maize inbreds (AM126), which were genotyped by the genotyping-by-sequencing (tGBS) method. We performed genetic characterization and association analysis related to gra ...
DOI:
10.1186/s12863-018-0669-9
PubMed:
30139352
PubMed Central:
PMC6108135

16. Genetic dissection and fine mapping of a novel dt gene associated with determinate growth habit in sesame

Author:
Yanxin Zhang; Linhai Wang; Yuan Gao; Donghua Li; Jingyin Yu; Rong Zhou; Xiurong Zhang
Source:
BMC genetics 2018 v.19 no.1 pp. 38
ISSN:
1471-2156
Subject:
Sesamum indicum; breeding; cultivars; determinate growth; genetic analysis; genotyping by sequencing; mechanization; microsatellite repeats; molecular cloning; oil crops; recessive genes; single nucleotide polymorphism
Abstract:
... BACKGROUND: As an important oil crop, growth habit of sesame (Sesamum indicum L.) is naturally indeterminate, which brings about asynchronous maturity of capsules and causes loss of yield. RESULTS: The genetic basis of determinate growth habit in sesame was investigated by classical genetic analysis through multiple populations, results revealed that it was controlled by an unique recessive gene. ...
DOI:
10.1186/s12863-018-0614-y
PubMed:
29902971
PubMed Central:
PMC6003200

17. Genetic diversity and ex situ conservation of Loropetalum subcordatum, an endangered species endemic to China

Author:
Bai-Jun Li; Jie-Yu Wang; Zhong-Jian Liu; Xue-Ying Zhuang; Jiu-Xiang Huang
Source:
BMC genetics 2018 v.19 no.1 pp. 12
ISSN:
1471-2156
Subject:
DNA; Loropetalum; asexual reproduction; endangered species; ex situ conservation; genetic variation; habitats; plants (botany); polymerase chain reaction; population size; seeds; surveys; China
Abstract:
... BACKGROUND: Loropetalum subcordatum is an endangered species endemic to China that is characterized by narrow distribution, small population size, and delayed fertilization. However, the genetic diversity of the entire extant natural and ex situ populations has not been assessed to date. In this study, we evaluated the genetic diversity and structure of six natural populations and a single ex situ ...
DOI:
10.1186/s12863-018-0599-6
PubMed:
29439656
PubMed Central:
PMC5812050

18. Genetic diversity and population structure analyses of Plectranthus edulis (Vatke) Agnew collections from diverse agro-ecologies in Ethiopia using newly developed EST-SSRs marker system

Author:
Fekadu Gadissa; Kassahun Tesfaye; Kifle Dagne; Mulatu Geleta
Source:
BMC genetics 2018 v.19 no.1 pp. 92
ISSN:
1471-2156
Subject:
Plectranthus barbatus; alleles; breeding; breeding programs; expressed sequence tags; gene flow; genetic variation; genotype; in situ conservation; loci; microsatellite repeats; population structure; potatoes; tubers; variance; Ethiopia
Abstract:
... BACKGROUND: Plectranthus edulis (Vatke) Agnew (locally known as Ethiopian dinich or Ethiopian potato) is one of the most economically important edible tuber crops indigenous to Ethiopia. Evaluating the extent of genetic diversity within and among populations is one of the first and most important steps in breeding and conservation measures. Hence, this study was aimed at evaluating the genetic div ...
DOI:
10.1186/s12863-018-0682-z
PubMed:
30309314
PubMed Central:
PMC6182789

19. Genetic diversity of BoLA-DRB3 in South American Zebu cattle populations

Author:
Shin-nosuke Takeshima; Claudia Corbi-Botto; Guillermo Giovambattista; Yoko Aida
Source:
BMC genetics 2018 v.19 no.1 pp. 33
ISSN:
1471-2156
Subject:
Nellore; South Americans; alleles; amino acid motifs; antigens; cattle; exons; frequency distribution; gene frequency; genetic distance; genetic polymorphism; genetic variation; leukocytes; major histocompatibility complex; polymerase chain reaction; principal component analysis; provenance; taurine; zebu; zebu breeds
Abstract:
... BACKGROUND: Bovine leukocyte antigens (BoLAs) are used extensively as markers of disease and immunological traits in cattle. However, until now, characterization of BoLA gene polymorphisms in Zebu breeds using high resolution typing methods has been poor. Here, we used a polymerase chain reaction sequence-based typing (PCR-SBT) method to sequence exon 2 of the BoLA class II DRB3 gene from 421 catt ...
DOI:
10.1186/s12863-018-0618-7
PubMed:
29788904
PubMed Central:
PMC5964877

20. Genetic insight and mapping of the pod constriction trait in Virginia-type peanut

Author:
Abhinandan S. Patil; Sigal Popovsky; Yael Levy; Ye Chu; Josh Clevenger; Peggy Ozias-Akins; Ran Hovav
Source:
BMC genetics 2018 v.19 no.1 pp. 93
ISSN:
1471-2156
Subject:
Arachis hypogaea; agronomic traits; analysis of variance; chromosome mapping; cultivars; gene frequency; genetic background; genetic improvement; heritability; inbred lines; loci; marker-assisted selection; molecular cloning; peanuts; pods; recessive genes; single nucleotide polymorphism
Abstract:
... BACKGROUND: Pod constriction is an important descriptive and agronomic trait of peanut. For the in-shell Virginia marketing-type, this trait has commercial importance as well, since deeply constricted pods have a tendency to break, which makes them unmarketable. Classical genetic studies have indicated that pod constriction in peanut is controlled by one to four genes, depending on the genetic bac ...
DOI:
10.1186/s12863-018-0674-z
PubMed:
30340455
PubMed Central:
PMC6195699