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- Author:
- Lopes, Natália Lôres, et al. ; Campos, Diefrey Ribeiro; Machado, Marília Alves; Alves, Mariana Silva Revoredo; de Souza, Manuela Silva Gomes; da Veiga, Cristiano Chaves Pessoa; Merlo, Alexandre; Scott, Fábio Barbour; Fernandes, Julio Israel; Show all 9 Authors
- Source:
- BMC veterinary research 2019 v.15 no.1 pp. 137
- ISSN:
- 1746-6148
- Subject:
- cats; corn starch; creatinine; cytokines; gastrointestinal system; hematologic tests; liver; maleates; mixed breeds; monocytes; neutrophils; non-specific protein-tyrosine kinase; pH; placebos; pruritus; specific gravity; toxicity; urine; vomiting
- Abstract:
- ... BACKGROUND: Oclacitinib is a Janus kinase (JAK) 1 enzyme inhibitor and blocks JAK1-dependent cytokines and is used to control pruritus. Studies available in cats are very limited and as there is a potential role for oclacitinib in the control of pruritus in this specie, the aim of this study was to evaluate the safety and clinical effects of oral oclacitinib maleate in healthy cats. RESULTS: Thirt ...
- DOI:
- 10.1186/s12917-019-1893-x
- PubMed:
- 31068210
- PubMed Central:
- PMC6506962
-
https://dx.doi.org/10.1186/s12917-019-1893-x