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- Keller, Janine, et al. Show all 8 Authors
- BMC veterinary research 2012 v.8 no.1 pp. 356
- biopsy; biosynthesis; carnitine; cations; dairy cows; early lactation; energy balance; energy deprivation; enzymes; fatty acid composition; fatty acids; free fatty acids; gene expression; gene targeting; genes; hepatocytes; liver; messenger RNA; oxidation; pregnancy; receptors; rodents; swine; transcription factors; transporters
- ... BACKGROUND: In rodents and pigs, it has shown that carnitine synthesis and uptake of carnitine into cells are regulated by peroxisome proliferator-activated receptor α (PPARA), a transcription factor which is physiologically activated during fasting or energy deprivation. Dairy cows are typically in a negative energy balance during early lactation. We investigated the hypothesis that genes of carn ...
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