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- Barr, Justinn; Gordon, Daniel; Schedl, Paul; Deshpande, Girish
- BioEssays 2015 v.37 no.3 pp. 278-283
- chromosome elimination, etc ; Sertoli cells; Y chromosome; etiology; germ cells; induced pluripotent stem cells; male fertility; males; mice; phenotype; xenotransplantation; Show all 11 Subjects
- ... Ramathal et al. have employed an elegant xenotransplantation technique to study the fate of human induced pluripotent stem cells (hiPSCs) from fertile males and from males carrying Y chromosome deletions of the azoospermia factor (AZF) region. When placed in a mouse testis niche, hiPSCs from fertile males differentiate into germ cell‐like cells (GCLCs). Highlighting the crucial role of cell autono ...
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