Journal name: Biochemical and biophysical research communications / Publication year rev: 7981-2019 / Subject: biotin / Subject term: biotin

Author:: Zhaoxiang Liu; Hua Zhang; Hong Xia; Baocheng Wang; Renwen Zhang; Qun Zeng; Lingzhi Guo; Kui Shen; BaTa Wang; Yanheng Zhong; Zhizhong Li; Guodong Sun
Source:: Biochemical and biophysical research communications 2019 v.512 no.2 pp. 367-372
ISSN:: 0006-291X
Subject:: CD8-positive T-lymphocytes; animal injuries; animal models; biotin; cerebrospinal fluid; cytokines; enzyme-linked immunosorbent assay; flow cytometry; humans; infectious diseases; inflammation; mice; permeability; spinal cord; staining
Abstract:: ... Perforin plays an important role in autoimmune and infectious diseases, but its function in immune inflammatory responses after spinal cord injury (SCI) has received insufficient attention. The goal of this study is to determine the influence of perforin after spinal cord injury (SCI) on secondary inflammation. Compared recovery from SCI in perforin knockout (Prf1−/−) and wild-type(WT)mice, WT mic ...
DOI:: 10.1016/j.bbrc.2019.03.002
: https://doi.org/10.1016/j.bbrc.2019.03.002

Author:: Xueyuan Yu; Xiangyu Liu; Rui Wang; Lu Wang
Source:: Biochemical and biophysical research communications 2019 v.512 no.4 pp. 825-831
ISSN:: 0006-291X
Subject:: Western blotting; apoptosis; biotin; caspase-3; cholecystokinin; endothelial cells; flow cytometry; hemangioma; infancy; luciferase; non-coding RNA; pathogenesis; precipitin tests; proliferating cell nuclear antigen; tissues; viability
Abstract:: ... Hemangioma (HA) is the most common benign vascular neoplasm of infancy that is resulted from abnormal proliferation of endothelial cells. Recent studies demonstrated that long non-coding RNAs (lncRNAs) were closely related to the pathogenesis of HA. LncRNA Nuclear enriched abundant transcript 1 (NEAT1) was involved in multiple tumor formation and biological behaviors of endothelial cells. However, ...
DOI:: 10.1016/j.bbrc.2019.03.084
: https://doi.org/10.1016/j.bbrc.2019.03.084

Author:: Tsubasa Hashimoto; Yuxin Ye; Mihoko Ui; Tomohisa Ogawa; Takashi Matsui; Yoshikazu Tanaka
Source:: Biochemical and biophysical research communications 2019 v.514 no.1 pp. 31-36
ISSN:: 0006-291X
Subject:: Todarodes pacificus; X-ray diffraction; biotin; chemical bonding; crystallization; crystals; encapsulation; engineering; green fluorescent protein; hemocyanin; ligands; nickel; nitrilotriacetic acid; protein subunits; streptavidin
Abstract:: ... Encapsulation of guest molecules into the vacant space of biomacromolecular crystals has been utilized for various purposes including functioning as a protein container to protect against physical stress and structural determination of the guest. Todarodes pacificus hemocyanin (TpHc) is a hollow cylindrical decameric protein complex with an inner space 110 Å in diameter and 160 Å in height. In the ...
DOI:: 10.1016/j.bbrc.2019.04.062
: https://doi.org/10.1016/j.bbrc.2019.04.062

Author:: Lulu Wang; Yuanyuan Chen; Fei Shang; Wei Liu; Jing Lan; Peng Gao; Nam-Chul Ha; Ki Hyun Nam; Yuesheng Dong; Chunshan Quan; Yongbin Xu
Source:: Biochemical and biophysical research communications 2019 v.520 no.3 pp. 538-543
ISSN:: 0006-291X
Subject:: Klebsiella pneumoniae; X-ray diffraction; active sites; biosynthesis; biotin; carboxylesterase; crystal structure; disulfides; gel chromatography; pathogens; research
Abstract:: ... The BioH carboxylesterase which is a typical α/β-hydrolase enzyme involved in biotin synthetic pathway in most bacteria. BioH acts as a gatekeeper and blocks the further elongation of its substrate. In the pathogen Klebsiella pneumoniae, BioH plays a critical role in the biosynthesis of biotin. To better understand the molecular function of BioH, we determined the crystal structure of BioH from K. ...
DOI:: 10.1016/j.bbrc.2019.10.050
: https://doi.org/10.1016/j.bbrc.2019.10.050

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