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- Yan, Yumeng; Lou, Yan; Kong, Juan
- Biochemical and biophysical research communications 2019 v.510 no.3 pp. 352-357
- myosin light chains, etc ; animal models; bone marrow transplant; edema; inflammation; knockout mutants; lipopolysaccharides; lungs; lymphocytes; mice; mortality; neutrophils; phosphorylation; respiratory tract diseases; sepsis (infection); Show all 15 Subjects
- ... Acute lung injury (ALI) is a type of diffuse lung inflammation with a high mortality rate. Studies show that miR-155 plays an important role in inflammation. Here, we investigated the role of miR-155 in lipopolysaccharide (LPS)-induced ALI. The mice with bone marrow transplantation between MiR-155 knockout and wild-type were used as animal models of LPS-induced sepsis. In response to LPS injection ...