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- Du, Juan, et al. Show all 10 Authors
- Biochemical and biophysical research communications 2014 v.446 pp. 187-194
- animal models; animal ovaries; cadherins; disease course; epithelium; estrogen receptors; gene expression regulation; neoplasm cells; ovarian neoplasms; patients; risk factors; signal transduction
- ... Kindlin-2 has been known to promote most cancer progression through regulation of multiple signaling pathways. However, a novel tumor suppressive role of Kindlin-2 was identified in serous epithelial ovarian cancer progression, which sharply contrasts to the tumor promoting roles for Kindlin-2 in most other cancers. While we demonstrated that Kindlin-2 was highly expressed in control tissues, a dr ...