Journal name: Biochemical and biophysical research communications / Publication Year: 2019 / Subject term: CD8-positive T-lymphocytes

Author:: Zhaoxiang Liu; Hua Zhang; Hong Xia; Baocheng Wang; Renwen Zhang; Qun Zeng; Lingzhi Guo; Kui Shen; BaTa Wang; Yanheng Zhong; Zhizhong Li; Guodong Sun
Source:: Biochemical and biophysical research communications 2019 v.512 no.2 pp. 367-372
ISSN:: 0006-291X
Subject:: CD8-positive T-lymphocytes; animal injuries; animal models; biotin; cerebrospinal fluid; cytokines; enzyme-linked immunosorbent assay; flow cytometry; humans; infectious diseases; inflammation; mice; permeability; spinal cord; staining
Abstract:: ... Perforin plays an important role in autoimmune and infectious diseases, but its function in immune inflammatory responses after spinal cord injury (SCI) has received insufficient attention. The goal of this study is to determine the influence of perforin after spinal cord injury (SCI) on secondary inflammation. Compared recovery from SCI in perforin knockout (Prf1−/−) and wild-type(WT)mice, WT mic ...
DOI:: 10.1016/j.bbrc.2019.03.002
: https://doi.org/10.1016/j.bbrc.2019.03.002

Author:: Trang Thi Thu Hau; Midori Nakamura-Hoshi; Yoshiaki Kanno; Takushi Nomura; Masako Nishizawa; Sayuri Seki; Hiroshi Ishii; Ai Kawana-Tachikawa; William W. Hall; Lan Anh Nguyen Thi; Tetsuro Matano; Hiroyuki Yamamoto
Source:: Biochemical and biophysical research communications 2019 v.512 no.2 pp. 213-217
ISSN:: 0006-291X
Subject:: CD8-positive T-lymphocytes; Human immunodeficiency virus; Macaca mulatta; Simian immunodeficiency virus; alleles; antigens; haplotypes; major histocompatibility complex; mutation; nucleotide sequences; virus replication
Abstract:: ... In human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections, host major histocompatibility complex class I (MHC-I) genotypes have a great impact on viral replication and MHC-I-associated viral genome mutations are selected under CD8+ T-cell pressure. Association of MHC-I genotypes with HIV/SIV control has been investigated at MHC-I allele levels but not fully at haplot ...
DOI:: 10.1016/j.bbrc.2019.03.003
: https://doi.org/10.1016/j.bbrc.2019.03.003

Author:: Yulong Xia; Tatsukuni Ohno; Naoto Nishii; Arundhati Bhingare; Hidetake Tachinami; Yoshihisa Kashima; Shigenori Nagai; Hirohisa Saito; Susumu Nakae; Miyuki Azuma
Source:: Biochemical and biophysical research communications 2019 v.518 no.2 pp. 331-336
ISSN:: 0006-291X
Subject:: CD8-positive T-lymphocytes; chemokines; colorectal neoplasms; dendritic cells; immunotherapy; interleukin-1; models; neutrophils; research
Abstract:: ... Interleukin-33 (IL-33) is a nuclear-associated cytokine of the IL-1 family. IL-33 and its receptor ST2 axis exert conflicting anti-tumor and pro-tumor effects in various tumors. In this study, we examined the role of endogenously produced IL-33 in the colon-26 tumor model, in which involvement of the IL-33:ST2 pathway was negligible on the tumor side. We found that the generation of regulatory T c ...
DOI:: 10.1016/j.bbrc.2019.08.058
: https://doi.org/10.1016/j.bbrc.2019.08.058

Author:: Yanli Lu; Linlin Wang; Jian Zhang; Jun Li; Guohua Wan
Source:: Biochemical and biophysical research communications 2019 v.516 no.3 pp. 1007-1012
ISSN:: 0006-291X
Subject:: B-lymphocytes; CD8-positive T-lymphocytes; antigen-presenting cells; colorectal neoplasms; cytotoxicity; epithelium; fecal bacteria; humans; immune response; inducible nitric oxide synthase; metabolites; monocytes; patients; viability
Abstract:: ... Commensal microbiota modulates the anti-tumor immune response and alters the tumor infiltration of T cells in numerous human malignancies. Moreover, the existence of commensals and microbial metabolites has been directly observed inside numerous epithelial tumors. Their effects on the host immune system, independent of the pre-existing malignancy, are not completely understood. To resolve this iss ...
DOI:: 10.1016/j.bbrc.2019.06.078
: https://doi.org/10.1016/j.bbrc.2019.06.078

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