U.S. flag

An official website of the United States government

PubAg

Main content area

You searched for: Author "Xia, Hong" Remove constraint Author: "Xia, Hong" Journal Biochemical and biophysical research communications Remove constraint Journal: Biochemical and biophysical research communications
Start Over

Search

2  Search Results

1 - 2 of 2
Number of results to display per page

Search Results

1. CD8 T cell-derived perforin aggravates secondary spinal cord injury through destroying the blood-spinal cord barrier

Author:
Xia, Hong,   et al.   ; Liu, Zhaoxiang; Zhang, Hua; Wang, Baocheng; Zhang, Renwen; Zeng, Qun; Guo, Lingzhi; Shen, Kui; Wang, BaTa; Zhong, Yanheng; Li, Zhizhong; Sun, Guodong;     Show all 12 Authors
Source:
Biochemical and biophysical research communications 2019 v.512 no.2 pp. 367-372
ISSN:
0006-291X
Subject:
CD8-positive T-lymphocytes; animal injuries; animal models; biotin; cerebrospinal fluid; cytokines; enzyme-linked immunosorbent assay; flow cytometry; humans; infectious diseases; inflammation; mice; permeability; spinal cord; staining
Abstract:
... Perforin plays an important role in autoimmune and infectious diseases, but its function in immune inflammatory responses after spinal cord injury (SCI) has received insufficient attention. The goal of this study is to determine the influence of perforin after spinal cord injury (SCI) on secondary inflammation. Compared recovery from SCI in perforin knockout (Prf1−/−) and wild-type(WT)mice, WT mic ...
DOI:
10.1016/j.bbrc.2019.03.002

2. K562 cell-derived exosomes suppress the adhesive function of bone marrow mesenchymal stem cells via delivery of miR-711

Author:
You, Xia-Hong,   et al.   ; Jiang, Yu-Huan; Liu, Jing; Lin, Jin; Li, Shu-Qi; Xu, Yan-Mei; Min, Qing-Hua; Zhong, Qiong-Hui; Sun, Fan; Li, Jing; Liao, Kai-Li; Qin, Ting-Yu; Zhao, Cui; Huang, Bo; Wang, Xiao-Zhong;     Show all 15 Authors
Source:
Biochemical and biophysical research communications 2020 v.521 no.3 pp. 584-589
ISSN:
0006-291X
Subject:
adhesion; bone marrow; coculture; exosomes; leukemia; microRNA; research
Abstract:
... A failure of bone marrow mesenchymal stem cells (BM-MSCs) to adhere to hematopoietic cells is an essential cause of the progression of chronic myelogenous leukemia and is also a cause of failure of bone marrow (BM) transplantation, but the exact mechanisms of this have not been fully elucidated. Recent studies have indicated that microRNAs (miRNAs) are contained in leukemia-derived exosomes and ar ...
DOI:
10.1016/j.bbrc.2019.10.096