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- Gangopadhyay, Soumyashree A.; Cox, Kurt J.; Manna, Debasish; Lim, Donghyun; Maji, Basudeb; Zhou, Qingxuan; Choudhary, Amit
- Biochemistry 2019 v.58 no.4 pp. 234-244
- chromosome translocation, etc ; DNA; adaptive immunity; bacteria; biomedical research; biotechnology; chromatin; enzymes; epigenetics; gene editing; gene therapy; genes; genomics; genotoxicity; image analysis; loci; models; Show all 17 Subjects
- ... The CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system is an adaptive immune system of bacteria that has furnished several RNA-guided DNA endonucleases (e.g., Cas9) that are revolutionizing the field of genome engineering. Cas9 is being used to effect genomic alterations as well as in gene drives, where a particular trait may be propagated through a targeted species popul ...