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- Mosesso, Richard; Dougherty, Dennis A.; Lummis, Sarah C. R.
- Biochemistry 2018 v.57 no.27 pp. 4036-4043
- gain-of-function mutation, etc ; Erwinia; Xenopus laevis; calcium; electrophysiology; eukaryotic cells; ion channels; models; mutants; oocytes; proline; receptors; Show all 12 Subjects
- ... Erwinia ligand-gated ion channel (ELIC) is a bacterial homologue of vertebrate pentameric ligand-gated ion channels (pLGICs) and has proven to be a valuable model for understanding the structure and function of this important protein family. There is nevertheless still a question about whether molecular details can be accurately extrapolated from this protein to those found in eukaryotes. Here we ...