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- Doerner, Pamela
Arden; Sousa, Marcelo C.
- Biochemistry 2017 v.56 no.24 pp. 3142-3149
- Escherichia coli; Gram-negative bacteria; crystal structure; mechanistic models; molecular dynamics; outer membrane proteins
- ... BamA is an essential component of the β-barrel assembly machine (BAM) that is responsible for insertion and folding of β-barrel outer membrane proteins (OMPs) in Gram-negative bacteria. BamA is an OMP itself, and its β-barrel transmembrane domain is thought to catalyze OMP insertion and folding, although the molecular mechanism remains poorly understood. Crystal structures of BamA and complementar ...
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