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- Huang, Mei, et al. Show all 17 Authors
- Biochemistry 2018 v.57 no.1 pp. 149-159
- double-stranded RNA; half life; messenger RNA; models; nucleotide sequences; nucleotides; rabbits; therapeutics; viral proteins
- ... Minus-one programmed ribosomal frameshifting (−1 PRF) allows the precise maintenance of the ratio between viral proteins and is involved in the regulation of the half-lives of cellular mRNAs. Minus-one ribosomal frameshifting is activated by several stimulatory elements such as a heptameric slippery sequence (X XXY YYZ) and an mRNA secondary structure (hairpin or pseudoknot) that is positioned 2–8 ...