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- Wantuch, Paeton L., et al. Show all 27 Authors
- Biochemistry 2015 v.54 no.27 pp. 4163-4166
- CCR7 receptor; T-lymphocytes; binding sites; chemokine CCL19; chemokine CCL21; lymphatic system
- ... CCL19 and CCL21 are chemokines involved in the trafficking of immune cells, particularly within the lymphatic system, through activation of CCR7. Concurrent expression of PSGL-1 and CCR7 in naive T-cells enhances recruitment of these cells to secondary lymphoid organs by CCL19 and CCL21. Here the solution structure of CCL19 is reported. It contains a canonical chemokine domain. Chemical shift mapp ...
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