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- Gusakov, Alexander V.; Dotsenko, Anna S.; Rozhkova, Aleksandra M.; Sinitsyn, Arkady P.
- Biochimie 2016
- Talaromyces verruculosus, etc ; Myceliophthora thermophila; active sites; biocatalysts; biodegradation; cellulases; cellulose; enzyme activity; fungi; mechanistic models; site-directed mutagenesis; Show all 11 Subjects
- ... Cellobiohydrolases (CBHs), belonging to glycoside hydrolase families 6 and 7 (GH6 and GH7), are the major components of cellulase systems of filamentous fungi involved in biodegradation of cellulose in nature. Previous studies demonstrated that N-linked glycans in the catalytic domains of GH7 CBHs significantly affect the enzyme activity against cellulosic substrates. The influence of N-linked gly ...