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- Kim, Kyu-Won, et al. Show all 5 Authors
- Biochimie 2012 v.94 no.3 pp. 734-740
- angiogenesis; endothelial cells; hypoxia; insulin-like growth factor II; retina; retinal diseases; vascular endothelial growth factors
- ... In ocular development, retinal physiological hypoxia in response to the retinal metabolic activity controls retinal vascular development, which is regulated by variable angiogenic factors. Herein, we demonstrated that hypoxia-induced IGF-II could contribute to retinal vascularization in ocular development. In the developing retina, IGF-II expression appears to be predominant on retinal vessels, wh ...