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You searched for: Author "Kim, Kyu-Won" Remove constraint Author: "Kim, Kyu-Won" Journal Biochimie Remove constraint Journal: Biochimie Subject vascular endothelial growth factors Remove constraint Subject: vascular endothelial growth factors
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1. Hypoxia-induced insulin-like growth factor II contributes to retinal vascularization in ocular development

Author:
Kim, Kyu-Won,   et al.   ; Kim, Jin Hyoung; Park, Sung Wook; Yu, Young Suk; Kim, Jeong Hun;     Show all 5 Authors
Source:
Biochimie 2012 v.94 no.3 pp. 734-740
ISSN:
0300-9084
Subject:
angiogenesis; endothelial cells; hypoxia; insulin-like growth factor II; retina; retinal diseases; vascular endothelial growth factors
Abstract:
... In ocular development, retinal physiological hypoxia in response to the retinal metabolic activity controls retinal vascular development, which is regulated by variable angiogenic factors. Herein, we demonstrated that hypoxia-induced IGF-II could contribute to retinal vascularization in ocular development. In the developing retina, IGF-II expression appears to be predominant on retinal vessels, wh ...
DOI:
10.1016/j.biochi.2011.11.003