Jump to Main Content
- Luz-Crawford, Patricia, et al. Show all 6 Authors
- Biochimie 2017 v.136 pp. 55-58
- homeostasis; immunosuppression; osteoblasts; peroxisome proliferator-activated receptors; stem cells; therapeutics; transcription factor NF-kappa B
- ... Peroxisome proliferator-activated receptors (PPARs) have emerged as key regulators of physiological and immunological processes. Recently, one of their members PPARβ/δ has been identified as major player in the maintenance of bone homeostasis, by promoting Wnt signalling activity in osteoblast and mesenchymal stem cells (MSC). PPARβ/δ not only controls the fate of MSC but also regulates their immu ...