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You searched for: Journal name Biological trace element research Remove constraint Journal name: Biological trace element research Publication year rev 7978-2022 Remove constraint Publication year rev: 7978-2022 Source 2022 v.200 no.4 Remove constraint Source: 2022 v.200 no.4
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1. Anti-Hyperuricemic Effect of Iron Oxide Nanoparticles against Monosodium Urate Crystals Induced Gouty Arthritis in BALB/c Mice

Author:
Mubin Mustafa Kiyani; Nurain Baig Moghul; Maisra Azhar Butt; Hamza Rehman; Ramsha Masood; Tausif Ahmed Rajput; Syed Ali Imran Bokhari
Source:
Biological trace element research 2022 v.200 no.4 pp. 1659-1666
ISSN:
0163-4984
Subject:
alkaline phosphatase; blood; creatinine; gout; histopathology; hyperuricemia; iron oxides; kidneys; lipid composition; liver; liver function; muscles; renal function; research; trace elements; urea; uric acid
Abstract:
... Iron oxide nanoparticles (FeO-NPs) exhibit exceptional properties which can be utilized in various aspects of biological sciences. In this experiment we investigated the anti-gout effectiveness of FeO-NPs in mice. BALB/c mice were induced gouty arthritis by administering monosodium urate (MSU) crystals. These gout induced mice were treated with three different concentrations of FeO-NPs (5 ppm, 10  ...
DOI:
10.1007/s12011-021-02769-0

2. Biomagnification of Copper Along the Aquatic Food Chain (Artemia franciscana, Danio rerio, and Astronotus ocellatus)

Author:
Maryam Mirzaei VandKhanghah; Aliakbar Hedayati; Samaneh Nazeri; Hamid Mohammadi Azarm; Rasoul Ghorbani
Source:
Biological trace element research 2022 v.200 no.4 pp. 1854-1860
ISSN:
0163-4984
Subject:
Artemia franciscana; Astronotus; Danio rerio; alanine transaminase; aspartate transaminase; bile; bioaccumulation; copper sulfate; edema; food chain; glucose; histopathology; human health; hyperemia; lethal concentration 50; liver; necrosis; pollution; portal vein; research; toxicity
Abstract:
... Nowadays, pollution of aquatic ecosystems with heavy metals is one of the most important environmental challenges due to toxicity, stability, and bioaccumulation in the environment. Heavy metals accumulate in aquatics and plant tissues and can eventually threaten human health by transmission into the food chain. For this reason, in the present study, the effect of copper sulfate (CuSO₄) and its tr ...
DOI:
10.1007/s12011-021-02781-4

3. Borax Pentahydrate and Disodium Pentaborate Decahydrate Are Candidates as Anti-leukemic Drug Components by Inducing Apoptosis and Changing Bax/Bcl-2 Ratio in HL-60 Cell Line

Author:
Tuğba Erkmen; Belgin Sert Serdar; Halil Ateş; Mehmet Korkmaz; Semra Koçtürk
Source:
Biological trace element research 2022 v.200 no.4 pp. 1608-1616
ISSN:
0163-4984
Subject:
antineoplastic agents; apoptosis; borax; boron; boronic acids; cell lines; cell viability; drug development; flow cytometry; human nutrition; myeloid leukemia; myeloma; propidium; research; therapeutics; toxicity; toxicity testing
Abstract:
... Acute myeloid leukemia (AML) is the most common form of acute leukemia and has the lowest 5-year survival rates. Current treatment strategies do not meet the expectations also. Therefore, there is a need to improve therapeutic approaches still. Boron, which is a natural trace element in human diet, is gaining attention with its important roles in cellular processes for the development of new anti- ...
DOI:
10.1007/s12011-021-02802-2

4. Damaging effects of TiO2 nanoparticles on the ovarian cells of Bombyx mori

Author:
Yilong Fang; Mingli Dai; Wentao Ye; Fanchi Li; Haina Sun; Jing Wei; Bing Li
Source:
Biological trace element research 2022 v.200 no.4 pp. 1883-1891
ISSN:
0163-4984
Subject:
Bombyx mori; DNA damage; cell lines; cell viability; dose response; drugs; industry; inflammation; interleukin-6; research; superoxide dismutase; titanium dioxide; toxicity; trace elements; transcription (genetics)
Abstract:
... As a new type of biologically compatible material, TiO₂ NPs are widely used in the industry as additives, drug carriers, and components of skin care products. Due to their wide use, residual TiO₂ NPs in the environment are a safety concern that has attracted extensive attention. In this study, the ovarian cell line BmN of the model organism Bombyx mori was used to reveal the damaging effects of Ti ...
DOI:
10.1007/s12011-021-02760-9

5. Dietary Influences on Urinary Fluoride over the Course of Pregnancy and at One-Year Postpartum

Author:
Gina A. Castiblanco-Rubio; Teresa V. Muñoz-Rocha; Martha M. Téllez-Rojo; Adrienne S. Ettinger; Adriana Mercado-García; Karen E. Peterson; Howard Hu; Alejandra Cantoral; E. Angeles Martínez-Mier
Source:
Biological trace element research 2022 v.200 no.4 pp. 1568-1579
ISSN:
0163-4984
Subject:
biomarkers; calcium; electrodes; fluorides; food frequency questionnaires; pregnancy; regression analysis; research; specific gravity; table salt; trace elements
Abstract:
... Dietary factors are known to influence urinary fluoride (UF) levels in nonpregnant people. Maternal UF is used as a biomarker of fluoride exposure; however, dietary influences on UF during pregnancy are unknown. We compared UF levels and assessed the associations between UF and five select dietary influences in pregnancy vs. one-year postpartum: dietary fluoride (F), calcium intake from diet (Ca-d ...
DOI:
10.1007/s12011-021-02799-8

6. Dysregulation of Transcription Profile of Selenoprotein in Patients with Kashin-Beck Disease and Its Effect on Se Deficiency–Induced Chondrocyte Apoptosis

Author:
XiaoLi Yang; ZhaoFang Li; RongQiang Zhang; Di Zhang; YongMin Xiong; Chen Wang; XueNa Yang; Qiang Li
Source:
Biological trace element research 2022 v.200 no.4 pp. 1508-1517
ISSN:
0163-4984
Subject:
antioxidant activity; apoptosis; chondrocytes; research; selenium; selenocysteine; selenoproteins
Abstract:
... Kashin-Beck disease (KBD) is a chronic, degenerative osteoarthropathy related to selenium (Se) deficiency. Se participates in the synthesis of selenoprotein in the form of selenocysteine. In total, 25 selenoproteins, encoded by 25 genes, are currently found in humans; however, the effects of selenoprotein genes on chondrocyte apoptosis, particularly in apoptosis-related genes, remain poorly elucid ...
DOI:
10.1007/s12011-021-02772-5

7. Effect of Telmisartan on Arsenic-Induced (Sub-chronic) Perturbations in Redox Homeostasis, Pro-inflammatory Cascade and Aortic Dysfunction in Wistar Rats

Author:
B. Rudresh Gowda; N. Prakash; C. R. Santhosh; B. H. Pavithra; Rashmi Rajashekaraiah; M. L. Sathyanarayana; Suguna Rao; Prashantkumar Waghe; K. R. Anjan Kumar; G. R. Shivaprasad; Y. Muralidhar
Source:
Biological trace element research 2022 v.200 no.4 pp. 1776-1790
ISSN:
0163-4984
Subject:
antioxidant activity; aorta; aqueous solutions; arsenic; gene expression; histopathology; homeostasis; interleukin-6; lipid peroxidation; males; malondialdehyde; polysorbates; prostaglandin synthase; research; sodium; subchronic exposure; superoxide anion; telmisartan
Abstract:
... An experimental study was conducted in male Wistar rats to explore the antioxidant potential of telmisartan (an AT₁ receptor blocker) to overcome arsenic (‘As’)-induced perturbations in redox homeostasis pro-inflammatory cytokines, prostaglandin-E₂ levels and aortic dysfunction in Wistar rats. Wistar rats were randomly divided into four groups of six each. Group-I served as untreated control, whil ...
DOI:
10.1007/s12011-021-02804-0

8. Exposures and Health Risks Associated with Elements in Diets from a Gold Mining Area

Author:
Ekpor Anyimah-Ackah; Isaac Williams Ofosu; Herman Erick Lutterodt; Godfred Darko
Source:
Biological trace element research 2022 v.200 no.4 pp. 1518-1530
ISSN:
0163-4984
Subject:
United States Environmental Protection Agency; X-radiation; arsenic; barium; calcium; cassava; corn; diet recall; fluorescence; gold; lead; nutritional adequacy; pollution; potassium; principal component analysis; public health; research; rice; risk; selenium; surveys; tomatoes; toxicity; yams; zinc; Ghana
Abstract:
... There has been a concern of metal contamination from the mining areas which could expose the population to toxic metal through consumption of food products in the regions. Therefore, the study was conducted to analyze 18 elements using X-ray fluorescence analyzer and to assess for metal exposure through dietary intakes. Dietary recall survey instrument was used to collect consumption, demographic, ...
DOI:
10.1007/s12011-021-02777-0

9. Health Risk Assessment of Essential and Toxic Metals in Canned/Pouched Food on Kitten and Adult Cats: an Animal Health Risk Assessment Adaptation Assay

Author:
Fulya Altınok-Yipel; Mustafa Yipel; İbrahim Ozan Tekeli
Source:
Biological trace element research 2022 v.200 no.4 pp. 1937-1948
ISSN:
0163-4984
Subject:
adults; animal health; health effects assessments; kidneys; kittens; liver; research; risk; risk assessment process; salmon; toxicity; tuna
Abstract:
... The main aim of this study was to determine the levels of Al, Cd, Cr, Cu, Fe, Hg, Mn, Ni, Pb, and Zn in commercial canned and pouched cat foods (salmon, tuna, liver, fish, and other aquatic products) and assess the potential health risks to kitten (≤ 1 years old) and adult cats (≥ 1 years old) associated with the recommended average consumption rate of labels. The study was also aimed to adapt the ...
DOI:
10.1007/s12011-021-02792-1

10. Induction of Cell Death in Pancreatic Tumors by Zinc and Its Fluorescence Chelator TSQ

Author:
Kinji Asahina
Source:
Biological trace element research 2022 v.200 no.4 pp. 1667-1676
ISSN:
0163-4984
Subject:
adenocarcinoma; cell death; chelating agents; death; fluorescence; humans; mice; mutation; neoplasm cells; organoids; pancreas; pancreatic neoplasms; research; zinc
Abstract:
... Pancreatic ductal adenocarcinoma is a devastating cancer and is the fourth-leading cause of cancer death in the USA. Zinc is abundant in the pancreas, but its role in pancreatic cancer remains elusive. The aim of this study is to determine effects of zinc chelators in pancreatic cancer. Pdx1Cʳᵉ and LSL-Krasᴳ¹²ᴰ mice expressing an oncogenic mutation of KRAS develop pancreatic intraepithelial neopla ...
DOI:
10.1007/s12011-021-02770-7

11. Investigation of Protein Biomarkers and Oxidative Stress in Pinirampus pirinampu Exposed to Mercury Species from the Madeira River, Amazon-Brazil

Author:
José Cavalcante Souza Vieira; Grasieli de Oliveira; Nubya Gonçalves Cavallini; Camila Pereira Braga; Jiri Adamec; Luiz Fabrício Zara; Marília Afonso Rabelo Buzalaf; Pedro de Magalhães Padilha
Source:
Biological trace element research 2022 v.200 no.4 pp. 1872-1882
ISSN:
0163-4984
Subject:
adenylate kinase; atomic absorption spectrometry; biomarkers; electrospray ionization mass spectrometry; enzyme activity; fish; fractionation; glyceraldehyde-3-phosphate dehydrogenase; lipid peroxidation; liver; mercury; mitochondria; muscle tissues; muscles; oxidative stress; proteome; research; rivers; toxicology; trace elements; triose-phosphate isomerase; two-dimensional gel electrophoresis; Amazonia
Abstract:
... In recent decades, the scientific community has widely debated the contamination of fish in the Amazon region by mercury species. As the diet of riverside populations in the Amazon region is based mainly on fish, these populations are exposed to mercurial species that can cause serious and irreversible damage to their health. The risks of consuming fish exposed to mercurial species in the Amazon r ...
DOI:
10.1007/s12011-021-02805-z

12. Nano-Bio Selenium Synthesized by Bacillus subtilis Modulates Broiler Performance, Intestinal Morphology and Microbiota, and Expression of Tight Junction’s Proteins

Author:
Fatholahi Ali; Khalaji Saeed; Hosseini Fatemeh
Source:
Biological trace element research 2022 v.200 no.4 pp. 1811-1825
ISSN:
0163-4984
Subject:
Bacillus subtilis; biosynthesis; body weight; breasts; bursa of Fabricius; duodenum; ileum; jejunum; liver; microorganisms; morphometry; occludins; particle size; research; selenium; sodium selenite; tight junctions; transmission electron microscopy
Abstract:
... A green and ecofriendly bio-based synthesis of nano selenium particles was performed using the Bacillus subtilis and the products were characterized by field emission scanning electron microscope (FESEM), dynamic light scattering (DLS) and transmission electron microscopy (TEM) methods. Dietary treatments included a control diet nonsupplemented with selenium and control diet supplemented with diff ...
DOI:
10.1007/s12011-021-02767-2

13. Organic Zinc and Copper Supplementation–Associated Changes in Gene Expression and Protein Profiles in Buck Spermatozoa

Author:
Venkata Krishnaiah Mayasula; Arangasamy Arunachalam; Selvaraju Sellappan; Pushpa Rani Guvvala; Jyotirmoy Ghosh
Source:
Biological trace element research 2022 v.200 no.4 pp. 1626-1639
ISSN:
0163-4984
Subject:
body weight; diet; genes; mechanism of action; protein composition; reproduction; research; roughage; semen; two-dimensional gel electrophoresis; zinc
Abstract:
... Mineral supplementation has greater impact on male reproduction; however, the mechanism of action has not been studied in detail. The present study was aimed to deal with the lacuna in mechanism of action of mineral supplementation on improvement in sperm characteristics. A group of 40 bucks (aged 5 months) were assigned to 10 groups (4 in each group) based on their body weight and fed with concen ...
DOI:
10.1007/s12011-021-02796-x

14. Parenteral Copper Administration at the Beginning of a Fixed-Time Artificial Insemination Protocol in Beef Cattle: Effect on Ovarian Function and Pregnancy Rates

Author:
Juan Patricio Anchordoquy; Santiago Nicolás Lorenti; Gustavo Sebastián Polero; Nicolás Agustín Farnetano; Diana Esther Rosa; Mariana Carolina Fabra; Ana Cristina Carranza-Martin; Noelia Nikoloff; Cecilia Cristina Furnus; Juan Mateo Anchordoquy
Source:
Biological trace element research 2022 v.200 no.4 pp. 1617-1625
ISSN:
0163-4984
Subject:
artificial insemination; beef; beef cattle; blood flow; copper; corpus luteum; estradiol; pregnancy rate; progesterone; research
Abstract:
... The aim of this study was to evaluate the association between plasma copper (Cu) concentration and ovarian function during a fixed-time artificial insemination (FTAI) protocol and the effect of parenteral Cu administration (100 mg) at the start of such protocol (day 0) on area of preovulatory follicle (APF); area of corpus luteum (ACL), plasma estradiol (E2), and progesterone (P4) concentrations; ...
DOI:
10.1007/s12011-021-02795-y

15. Rutin Ameliorates Cadmium-Induced Necroptosis in the Chicken Liver via Inhibiting Oxidative Stress and MAPK/NF-κB Pathway

Author:
Lili Liu; Liangyou Zhao; Yuan Liu; Xiaoli Yu; Xinyuan Qiao
Source:
Biological trace element research 2022 v.200 no.4 pp. 1799-1810
ISSN:
0163-4984
Subject:
anti-inflammatory activity; antioxidant activity; antioxidants; biomarkers; cadmium; caspase-8; heat stress; heat-shock protein 40; hepatotoxicity; histopathology; liver; liver function; necroptosis; oxidative stress; poisoning; research; rutin; trace elements
Abstract:
... Cadmium (Cd) is a recognized toxic metal and exerts serious hepatotoxicity in animals and humans. Rutin (RUT) is a dietary bioflavonoid with strong antioxidant and anti-inflammatory potential. However, little is known about the alleviating effect of RUT against Cd-induced liver necroptosis. The aim of this study was to ascertain the ameliorative mechanism of RUT on necroptosis triggered by Cd in c ...
DOI:
10.1007/s12011-021-02764-5

16. Selenium Alleviates Inflammation in Staphylococcus aureus-Induced Mastitis via MerTK-Dependent Activation of the PI3K/Akt/mTOR Pathway in Mice

Author:
Si-jie Chen; Chen-yuan Zhang; Di Yu; Chang-jie Lin; Hao-jun Xu; Chang-min Hu
Source:
Biological trace element research 2022 v.200 no.4 pp. 1750-1762
ISSN:
0163-4984
Subject:
Staphylococcus aureus; Western blotting; enzyme-linked immunosorbent assay; females; histopathology; human health; immunity; inflammation; interleukin-6; phosphatidylinositol 3-kinase; phosphorylation; research; selenium
Abstract:
... Mastitis caused by Staphylococcus aureus infection not only causes serious economic losses, but also affects human health. Se plays an important role in body immunity. However, the mechanisms by which Se regulates mastitis induced by S. aureus are still principally unknown. The purpose of this study is to investigate whether Se can inhibit mastitis induced by S. aureus through regulation of MerTK. ...
DOI:
10.1007/s12011-021-02794-z

17. Serum Copper and Zinc Concentrations and Cognitive Impairment in Older Adults Aged 60 Years and Older

Author:
Zonglin Gong; Wenlei Song; Minjun Gu
Source:
Biological trace element research 2022 v.200 no.4 pp. 1495-1501
ISSN:
0163-4984
Subject:
National Health and Nutrition Examination Survey; animals; blood serum; cognition; cognitive disorders; copper; mass spectrometry; research; zinc
Abstract:
... Epidemiological evidence on serum zinc and copper and cognitive impairment in older adults are not consistent. Results on serum zinc and copper and cognitive impairment in older adults from the National Health and Nutrition Examination Survey (NHANES) have not been reported. Data on serum zinc and copper and cognitive impairment from individuals ≥ 60 years of age were obtained from the 2011–2014 N ...
DOI:
10.1007/s12011-021-02765-4

18. Serum Levels of Selected Elements in Patients with Beta Thalassemia Major

Author:
Ayşe Şahin; Elif Öztürk Er; Ersoy Öz; Zeynep Yıldız Yıldırmak; Sezgin Bakırdere
Source:
Biological trace element research 2022 v.200 no.4 pp. 1502-1507
ISSN:
0163-4984
Subject:
biomarkers; blood serum; iron overload; mass spectrometry; patients; research; thalassemia; toxicity
Abstract:
... β-thalassemia major is a significant health problem in the world that obliges patient to repeated blood transfusions. Frequent transfusions cause toxic iron overload and the association between serum iron levels and β-thalassemia major have been extensively studied in literature. Nonetheless, data on trace elements is still limited. The aim of this work was to study the relationship between some t ...
DOI:
10.1007/s12011-021-02768-1

19. Small Heat Shock Protein’s Gene Expression Response to Iron Oxide Nanoparticles in the Brain

Author:
Mehdi Basaki; Kamran Keykavusi; Nazila Sahraiy; Ghasem Akbari; Marzieh Hejazi
Source:
Biological trace element research 2022 v.200 no.4 pp. 1791-1798
ISSN:
0163-4984
Subject:
chick embryos; eggs; gene expression; heat shock proteins; heat stress; iron oxides; models; research; stress response
Abstract:
... Small heat shock proteins (SHSPs) are conserved proteins that participate in many cellular functions like preventing protein aggregation and stress response. However, their role in responding to nanoparticles (NPs) has not yet been explained. We used a chicken embryo model to investigate the effects of two different forms of iron oxide-NPs (IONPs) on the mRNA expression of HSPB1, HSPB5, HSPB8, and ...
DOI:
10.1007/s12011-021-02761-8

20. The Occurrence of Lead in Animal Source Foods in Iran in the 2010s Decade: A Systematic Review

Author:
Zahra Sarlak; Hedayat Hosseini; Farhad Garavand; Reza Mohammadi; Milad Rouhi
Source:
Biological trace element research 2022 v.200 no.4 pp. 1917-1936
ISSN:
0163-4984
Subject:
animal-based foods; canned fish; eggs; fish; food safety; heavy metals; honey; lead; meat; milk; research; systematic review; toxicity; trace elements; Iran
Abstract:
... Lead is a toxic, non-biodegradable, and accumulative heavy metal released into the environment by natural and anthropogenic activities. Despite health concerns due to the consumption of lead-contaminated foods, no systematic and comprehensive review studies have been published about the lead occurrence in animal source foods in Iran. The present study aimed to review the papers investigating the P ...
DOI:
10.1007/s12011-021-02787-y