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- Uthus, Eric O.; Poellot, Rhonda A.
- Biological trace element research 1996 v.52 no.1 pp. 23
- folic acid; dose response; nickel; nutrient deficiencies; weight; body weight; blood chemistry; liver; kidneys; enzyme activity; amino acids; blood plasma; femur; rats; animal organs
- ... Because vitamin B12 and Ni are known to interact and because of the similar metabolic roles of vitamin B12 and folate, an experiment was performed to determine the effect of dietary folate on Ni deprivation in rats. A 2×2 factorially arranged experiment used groups of nine weanling Sprague-Dawley rats. Dietary variables were Ni, as NiCl2·6H2O, 0 or 1 μg/g; and folic acid, 0 or 2 mg/kg. The basal d ...