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- Fruehauf, Krista R., et al. Show all 6 Authors
- Biomacromolecules 2019 v.20 no.7 pp. 2703-2712
- bioavailability; copolymerization; hydrogels; lactate dehydrogenase; lactic acid; metabolites; nanoparticles; neoplasms; pH; polymers; temperature; therapeutics
- ... Stimuli-responsive polymers are an efficient means of targeted therapy. Compared to conventional agents, they increase bioavailability and efficacy. In particular, polymer hydrogel nanoparticles (NPs) can be designed to respond when exposed to a specific environmental stimulus such as pH or temperature. However, targeting a specific metabolite as the trigger for stimuli response could further elev ...