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- He, Chuanxin, et al. Show all 8 Authors
- Biomaterials 2017
- adenocarcinoma; aminolysis; antineoplastic agents; aqueous solutions; blood circulation; breast neoplasms; composite polymers; disulfide bonds; glutathione; humans; mice; moieties; nanomedicine; nanoparticles; neoplasm cells; paclitaxel; pharmacokinetics; polyethylene glycol; synthesis
- ... Block copolymer prodrugs (BCPs) have attracted considerable attentions in clinical translation of nanomedicine owing to their self-assembly into well-defined core-shell nanoparticles for improved pharmacokinetics, stability in blood circulation without drug leakage, and optimized biodistribution. However, a cascade of physiological barriers against specific delivery of drugs into tumor cells limit ...