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- Obeidat, Yusra M.; Cheng, Ming-Hao; Catandi, Giovana; Carnevale, Elaine; Chicco, Adam J.; Chen, Thomas W.
- Biosensors & bioelectronics 2019 v.133 pp. 39-47
- acidification; aerobiosis; assisted reproductive technologies; biopsy; biosensors; carbonic acid; glucose; glycolysis; horses; immunology; instrumentation; lactic acid; mitochondria; models; monitoring; neoplasms; oxidative phosphorylation; oxygen consumption
- ... Rates of cellular oxygen consumption (OCR) and extracellular acidification (ECAR) are widely used proxies for mitochondrial oxidative phosphorylation (OXPHOS) and glycolytic rate in cell metabolism studies. However, ECAR can result from both oxidative metabolism (carbonic acid formation) and glycolysis (lactate release), potentially leading to erroneous conclusions about metabolic substrate utiliz ...
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