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- Yang, Guang, et al. Show all 13 Authors
- Biotechnology letters 2012 v.34 no.5 pp. 839-847
- Foot-and-mouth disease virus; cattle; epitopes; foot-and-mouth disease; genes; guinea pigs; mice; neutralizing antibodies; recombinant proteins; vaccines; viruses
- ... To develop recombinant epitope vaccines against foot-and-mouth disease virus (FMDV), genes coding for six recombinant proteins (rP1–rP6) consisting of different combinations of B cell and T cell epitope from VP1 capsid protein (VP1) of type O FMDV were constructed and the 3D structure of these proteins analyzed. This revealed a surface-exposed RGD sequence of B cell epitopes in all six recombinant ...