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- Huang, Hongsheng; Soutyrine, Andrei; Rendulich, Jasmine; O’Rourke, Katherine; Balachandran, Aru
- Canadian journal of veterinary research 2011 v.75 no.1 pp. 69
- PrPSc proteins; Western blotting; autolysis; central nervous system; chemical precipitation; chronic wasting disease; detection; elks; enzyme-linked immunosorbent assay; lymphatic system; phosphotungstic acid; quantitative analysis; scrapie; sheep
- ... Tissues unsuitable for standard immunohistochemical and histopathological examinations for chronic wasting disease (CWD) in cervids and for scrapie in sheep are frequently submitted for testing. This study investigated the effects of experimental autolysis on the detection of abnormal prion protein (PrPsc) in lymphoid and central nervous system (CNS) tissues from elk and sheep. The PrPsc was detec ...