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- Miller, Ingrid, et al. Show all 5 Authors
- Canadian journal of veterinary research 2016 v.80 no.1 pp. 66-73
- cats; dogs; gelatin; gelatinase A; immunohistochemistry; metastasis; osteosarcoma
- ... Overexpression of matrix metalloproteinases (MMPs) has been associated with increased tumor aggressiveness and metastasis dissemination. We investigated whether the contrasting metastatic behavior of feline and canine osteosarcoma is related to levels and activities of MMP2 and MMP9. Zymography and immunohistochemistry were used to determine expression levels of MMP2 and MMP9 in canine and feline ...