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- Chang, Guanru, et al. Show all 7 Authors
- Carbohydrate polymers 2015 v.122 pp. 336-342
- adverse effects; antineoplastic activity; biocompatibility; chitosan; drug carriers; fluorouracil; hydrocolloids; neoplasm cells; pH; polyvinyl alcohol; synergism
- ... A self-healable chitosan(CS)/polyvinyl alcohol (PVA) hydrogel as an injectable drug carrier was first prepared in situ on tumor cells for effective and localized therapy. PVA molecules have a synergistic effect on the formation and maintenance of 3D network conformation of hydrogel. The hydrogel shows good biocompatibility and could be easily and rapidly formed. When loaded with fluorouracil (5-FU ...