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- Russo, Laura; Russo, Teresa; Battocchio, Chiara; Taraballi, Francesca; Gloria, Antonio; D’Amora, Ugo; De Santis, Roberto; Polzonetti, Giovanni; Nicotra, Francesco; Ambrosio, Luigi; Cipolla, Laura
- Carbohydrate research 2015 v.405 pp. 39-46
- X-ray photoelectron spectroscopy; cell adhesion; cell viability; contact angle; epitopes; galactose; hardness; humans; hydrophilicity; lectins; mechanical properties; moieties; stem cells; tissue engineering
- ... The grafting of galactose units onto poly(ε-caprolactone) (PCL) substrates by a wet chemistry two-step procedure is proposed. Even though a reduction of hardness from 0.58–0.31GPa to 0.12–0.05GPa is achieved, the chemical functionalization does not negatively affect the tensile modulus (332.2±31.3MPa and 328.5±34.7MPa for unmodified and surface-modified PCL, respectively) and strength (15.1±1.3MPa ...
- Cao, Xueyan; Tao, Lei; Wen, Shihui; Hou, Wenxiu; Shi, Xiangyang
- Carbohydrate research 2015 v.405 pp. 70-77
- biocompatibility; carbon nanotubes; cell viability; cellular microenvironment; chemical bonding; doxorubicin; drug carriers; drug therapy; fluorescein; hyaluronic acid; isothiocyanates; nanomedicine; neoplasm cells; neoplasms; pH; polyethyleneimine; receptors; viability assays; water solubility
- ... Development of novel drug carriers for targeted cancer therapy with high efficiency and specificity is of paramount importance and has been one of the major topics in current nanomedicine. Here we report a general approach to using multifunctional multiwalled carbon nanotubes (MWCNTs) as a platform to encapsulate an anticancer drug doxorubicin (DOX) for targeted cancer therapy. In this approach, p ...