Jump to Main Content
- Ma, Weirui; Mayr, Christine
- Cell 2018 v.175 no.6 pp. 1492-1506.e19
- RNA-binding proteins; amino acid sequences; endoplasmic reticulum; functional diversity; genes; granules; humans; membrane proteins; messenger RNA; protein-protein interactions
- ... Approximately half of human genes generate mRNAs with alternative 3′ untranslated regions (3′UTRs). Through 3′UTR-mediated protein-protein interactions, alternative 3′UTRs enable multi-functionality of proteins with identical amino acid sequence. While studying how information on protein features is transferred from 3′UTRs to proteins, we discovered that the broadly expressed RNA-binding protein T ...