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- Takada, Ayato, et al. Show all 48 Authors
- Cell 2018 v.174 no.4 pp. 938-952.e13
- Ebolavirus; cross reaction; data collection; epitopes; glycoproteins; in vitro studies; mice; models; monoclonal antibodies; natural killer cells; neutralization; neutralization tests; therapeutics; vaccines; virion; viruses
- ... Antibodies are promising post-exposure therapies against emerging viruses, but which antibody features and in vitro assays best forecast protection are unclear. Our international consortium systematically evaluated antibodies against Ebola virus (EBOV) using multidisciplinary assays. For each antibody, we evaluated epitopes recognized on the viral surface glycoprotein (GP) and secreted glycoprotei ...