Author: "DeMichele, Angela" / Journal: Cell / Subject: breast neoplasms and RNA / Text Availability: Full Text

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Author:: DeMichele, Angela M., et al. ; Nabet, Barzin Y.; Qiu, Yu; Shabason, Jacob E.; Wu, Tony J.; Yoon, Taewon; Kim, Brian C.; Benci, Joseph L.; Tchou, Julia; Marcotrigiano, Joseph; Minn, Andy J.; Show all 11 Authors
Source:: Cell 2017 v.170 pp. 352-366.e13
ISSN:: 0092-8674
Subject:: RNA; RNA-binding proteins; blood; breast neoplasms; exosomes; fibroblasts; inflammation; metastasis; neoplasm cells; patients; receptors; stoichiometry; therapeutics
Abstract:: ... Interactions between stromal fibroblasts and cancer cells generate signals for cancer progression, therapy resistance, and inflammatory responses. Although endogenous RNAs acting as damage-associated molecular patterns (DAMPs) for pattern recognition receptors (PRRs) may represent one such signal, these RNAs must remain unrecognized under non-pathological conditions. We show that triggering of str ...
DOI:: 10.1016/j.cell.2017.06.031
PubMed:: 28709002
PubMed Central:: PMC6611169
: http://dx.doi.org/10.1016/j.cell.2017.06.031