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- Schmid, Roland M., et al. Show all 10 Authors
- Cell 2017 v.170 pp. 1096-1108.e13
- T-lymphocytes; animal models; homeostasis; immune response; immunosuppression; immunotherapy; melanoma; mice; transcription factor NF-kappa B
- ... Regulatory T cells (Tregs) play a pivotal role in the inhibition of anti-tumor immune responses. Understanding the mechanisms governing Treg homeostasis may therefore be important for development of effective tumor immunotherapy. We have recently demonstrated a key role for the canonical nuclear factor κB (NF-κB) subunits, p65 and c-Rel, in Treg identity and function. In this report, we show that ...
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