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- Stanley, Robin E., et al. Show all 3 Authors
- Cell 2012 v.151 no.7 pp. 1501-1512
- autophagy; biogenesis; crystal structure; dimerization; proteins; yeasts
- ... Macroautophagy is a bulk clearance mechanism in which the double-membraned phagophore grows and engulfs cytosolic material. In yeast, the phagophore nucleates from a cluster of 20–30 nm diameter Atg9-containing vesicles located at a multiprotein assembly known as the preautophagosomal structure (PAS). The crystal structure of a 2:2:2 complex of the earliest acting PAS proteins, Atg17, Atg29, and A ...
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