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1. Clock genes in mammalian peripheral tissues

Author:
Balsalobre, Aurélio
Source:
Cell and tissue research 2002 v.309 no.1 pp. 193-199
ISSN:
0302-766X
Subject:
circadian rhythm; enzymes; gene expression; genes; hypothalamus; mammals; neurons; photoperiod; physiology; restricted feeding; structural proteins; transcription (genetics)
Abstract:
... For many years, neurons of the suprachiasmatic nucleus (SCN) in the hypothalamus were thought to contain the unique mammalian clock controlling circadian rhythmicity of peripheral tissues via neural and humoral signals. Surprisingly, the cloning and characterisation of mammalian clock genes have revealed that they are expressed in a circadian manner throughout the body. It is generally accepted no ...
DOI:
10.1007/s00441-002-0585-0
PubMed:
12111549

2. The pars tuberalis as a target of the central clock

Author:
Ross, Alexander W.; Morgan, Peter J.
Source:
Cell and tissue research 2002 v.309 no.1 pp. 163-171
ISSN:
0302-766X
Subject:
biological clocks; gene expression; genes; melatonin; neurosecretory system; photoperiod; physiology; receptors
Abstract:
... The pars tuberalis (PT) of the pituitary has emerged from being a gland of obscure and unknown function to a tissue of central importance to our understanding of how photoperiod regulates seasonal responses. The discovery of melatonin receptors on this gland first pointed to its involvement in seasonal physiology. However, the more recent demonstration of the expression of clock genes in the PT, s ...
DOI:
10.1007/s00441-002-0582-3
PubMed:
12111546