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- Stehle, Jörg H.; von Gall, Charlotte; Korf, Horst-Werner
- Cell and tissue research 2002 v.309 no.1 pp. 173-182
- adenosine; adenosine monophosphate; brain; cyclic AMP; gene expression; gene expression regulation; genes; melatonin; mice; pineal body; signal transduction
- ... In all vertebrates melatonin is rhythmically synthesised in the pineal gland and functions as a hormonal message encoding for the duration of darkness. This review focuses on the role of melatonin in the circadian organisation of mammals by comparing signal transduction mechanisms in the pineal organ, the suprachiasmatic nucleus and the hypophyseal pars tuberalis in melatonin-proficient (C3H) and ...
- Natesan, Arjun; Geetha, L.; Zatz, Martin
- Cell and tissue research 2002 v.309 no.1 pp. 35-45
- Drosophila; birds; calcium; cell culture; circadian rhythm; cryptochromes; cyclic nucleotides; genes; melatonin; mice; models; photoreceptors; pineal body; protein kinases; second messengers
- ... The avian pineal gland, like that of mammals, displays a striking circadian rhythm in the synthesis and release of the hormone melatonin. However, the pineal gland plays a more prominent role in avian circadian organization and differs from that in mammals in several ways. One important difference is that the pineal gland in birds is relatively autonomous. In addition to making melatonin, the avia ...