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- Robert, Stephanie M.; Sontheimer, Harald
- Cellular and molecular life sciences 2014 v.71 no.10 pp. 1839-1854
- amino acid transporters; brain; glutamic acid; homeostasis; neoplasms; patients; prognosis
- ... Malignant gliomas are relentless tumors that offer a dismal clinical prognosis. They develop many biological advantages that allow them to grow and survive in the unique environment of the brain. The glutamate transporters system xc⁻and excitatory amino acid transporters (EAAT) are emerging as key players in the biology and malignancy of these tumors. Gliomas manipulate glutamate transporter expre ...
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