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- YuanThese authors contributed equally., Fang; Bi, Ying; Siejka-Zielinska, Paulina; Zhou, Ying-Lin; Zhang, Xin-Xiang; Song, Chun-Xiao
- Chemical communications 2019 v.55 no.16 pp. 2328-2331
- RNA-directed DNA polymerase; chemical compounds; complementary DNA; introns; oxidation; thermal stability; transfer RNA
- ... 5-Methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC), two of the best-studied DNA modifications, play crucial roles in normal development and disease in mammals. Although 5-methylcytidine (m⁵C) and 5-hydroxymethylcytidine (hm⁵C) have also been identified in RNA, their distribution and biological function in RNA remain largely unexplored, due to the lack of suitable sequencing methods. Here, w ...