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- Craig, Ryan; Litvajova, Mili; Cronin, Sarah A.; Connon, Stephen J.
- Chemical communications 2018 v.54 no.72 pp. 10108-10111
- Lewis acids; Lewis bases; anhydrides; catalysts; catalytic activity; cations; chemical reactions; enantioselectivity; fluorides; nuclear magnetic resonance spectroscopy; organofluorine compounds; spectral analysis
- ... The asymmetric nucleophilic catalysis by fluoride ions at a carbon-based electrophile has been demonstrated for the first time. Using a library of ad hoc designed bifunctional phase-transfer catalysts in which both the anion and the cation are directly involved in the reaction, the desymmetrisation of meso-succinic and -glutaric anhydrides is possible. ¹⁹F NMR spectroscopic studies support the int ...