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- Hakk, H.; Larsen, G.; Bowers, J.
- Chemosphere 2004 v.54 no.10 pp. 1367
- flame retardant finishes; pollutants; pharmacokinetics; metabolism; tissue distribution; bioaccumulation; excretion; rats; laboratory animals; polybrominated biphenyls; oral administration; carbon; radionuclides; cannulas; bile ducts; males; toxicity testing; feces; thymus gland; adrenal glands; lungs; skin; metabolites; urine; bile; hydroxylation; mammals; mass spectrometry; gas chromatography
- ... A single oral dose of [14C] 1,2-bis(2,4,6-tribromophenoxy)ethane (BTBPE) was administered to conventional and bile-duct cannulated male Sprague-Dawley rats. Tissue disposition, excretion and metabolism was determined. BTBPE is a low-volume brominated flame retardant used in resins or plastics, and toxicity data in peer-reviewed journals is extremely limited. BTBPE was fairly insoluble in lipophili ...