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Chinese journal of natural medicines
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Publication year rev
7981-2019
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2019 v.17 no.4
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- Author:
- Wei WANG; Qing-Bin LIU; Wei JING
- Source:
- Chinese journal of natural medicines 2019 v.17 no.4 pp. 252-263
- ISSN:
- 1875-5364
- Subject:
- Astragalus membranaceus; Oriental traditional medicine; asthma; blood serum; childhood; children; density gradient centrifugation; flow cytometry; formononetin; genistein; high performance liquid chromatography; immunoglobulin E; interleukin-17; interleukin-23; isoquercitrin; isorhamnetin; kaempferol; lung function; mononuclear leukocytes; quercetin; remission; swine; therapeutics; transforming growth factor beta
- Abstract:
- ... Astragalus membranaceus may be a potential therapy for childhood asthma but its driving mechanism remains elusive. The main components of A. membranaceus were identified by HPLC. The children with asthma remission were divided into two combination group (control group, the combination of budesonide and terbutaline) and A. membranaceus group (treatment group, the combination of budesonide, terbutal ...
- DOI:
- 10.1016/S1875-5364(19)30029-9
- https://doi.org/10.1016/S1875-5364(19)30029-9
- Author:
- Cheng-Yao MA; Jia-Hui LU; Xiang LI; Xiao LIU; Jian-Wei CHEN
- Source:
- Chinese journal of natural medicines 2019 v.17 no.4 pp. 291-297
- ISSN:
- 1875-5364
- Subject:
- Annona squamosa; Oriental traditional medicine; acetogenins; cell lines; cytotoxicity; multiple drug resistance; seeds; spectral analysis
- Abstract:
- ... Eight new annonaceous acetogenins, squamotin A-D (1–4), annosquatin IV-V (5 and 6), muricin O (7) and squamosten B (8), together with four known ones (9–12) were isolated from the seeds of Annona squamosa. Their structures were elucidated by chemical methods and spectral data. The inhibitory activities of compound 1–9 against three multidrug resistance cell lines were evaluated. All tested compoun ...
- DOI:
- 10.1016/S1875-5364(19)30032-9
- https://doi.org/10.1016/S1875-5364(19)30032-9
- Author:
- Wen-Xia GONG; Yu-Zhi ZHOU; Xue-Mei QIN; Guan-Hua DU
- Source:
- Chinese journal of natural medicines 2019 v.17 no.4 pp. 264-274
- ISSN:
- 1875-5364
- Subject:
- Oriental traditional medicine; antineoplastic activity; apoptosis; calcium; cell viability; corticosterone; lactate dehydrogenase; mitochondria; neuroprotective effect; rats; rhizomes; sesquiterpenoids; therapeutics
- Abstract:
- ... Atractylenolide III (ATL-III), a sesquiterpene compound isolated from Rhizoma Atractylodis Macrocephalae, has revealed a number of pharmacological properties including anti-inflammatory, anti-cancer activity, and neuroprotective effect. This study aimed to evaluate the cytoprotective efficiency and potential mechanisms of ATL-III on corticosterone injured rat phaeochromocytoma (PC12) cells. Our re ...
- DOI:
- 10.1016/S1875-5364(19)30030-5
- https://doi.org/10.1016/S1875-5364(19)30030-5
- Author:
- Zhao-He LI; You ZHOU; You-Xiang DING; Qing-Long GUO; Li ZHAO
- Source:
- Chinese journal of natural medicines 2019 v.17 no.4 pp. 241-251
- ISSN:
- 1875-5364
- Subject:
- Oriental traditional medicine; adhesion; angiogenesis; carcinogenesis; cell adhesion molecules; cell differentiation; cell movement; cell proliferation; drugs; extracellular matrix; integrins; neoplasm cells; neoplasms
- Abstract:
- ... Integrin is a large family of cell adhesion molecules (CAMs) which involves in the interaction of cells/cells and cells/ extracellular matrix (ECM) to mediate cell proliferation, differentiation, adhesion, migration, etc. In recent years, aberrant expression of integrin has been clearly found in many tumor studies, indicating that integrin is closely related to tumor formation and development. Mea ...
- DOI:
- 10.1016/S1875-5364(19)30028-7
- https://doi.org/10.1016/S1875-5364(19)30028-7
- Author:
- Yong-Li HUA; Qi MA; Zi-Wen YUAN; Xiao-Song ZHANG; Wan-Ling YAO; Peng JI; Jun-Jie HU; Yan-Ming WEI
- Source:
- Chinese journal of natural medicines 2019 v.17 no.4 pp. 275-290
- ISSN:
- 1875-5364
- Subject:
- Oriental traditional medicine; S-adenosylmethionine; anemia; apoptosis; arachidonic acid; biochemical pathways; blood; chemical constituents of plants; cyclophosphamide; cysteine; databases; genes; genetic similarity; hematopoiesis; inflammation; iron; laboratory animals; liquid chromatography; mass spectrometry; metabolites; metabolomics; oxygen; pharmacology; phosphatidylcholines; protein-protein interactions; proteins; rats; reactive oxygen species; signal transduction; therapeutics
- Abstract:
- ... Danggui Buxue Tang (DBT) is a famous Chinese medicinal decoction. Mechanism of DBT action is wide ranging and unclear. Exploring new ways of treatment with DBT is useful. Sprague-Dawley(SD) rats were randomly divided into 3 groups including control (NC, Saline), the DBT (at a dose of 8.10 g−1), and blood deficiency(BD) (Cyclophosphamide (APH)-andCyclophosphamide(CTX)-induced anaemia). A metabolomi ...
- DOI:
- 10.1016/S1875-5364(19)30031-7
- https://doi.org/10.1016/S1875-5364(19)30031-7
- Author:
- Lin CHEN; Jia-Luo HUANG; Lei ZHANG; Hai-Yan TIAN; Sheng YIN
- Source:
- Chinese journal of natural medicines 2019 v.17 no.4 pp. 298-302
- ISSN:
- 1875-5364
- Subject:
- Jatropha podagrica; Oriental traditional medicine; anti-inflammatory activity; carbon; diterpenoids; inhibitory concentration 50; lipopolysaccharides; macrophages; nitric oxide; quercetin; spectroscopy; stems
- Abstract:
- ... Jatrogricaine A (1), a new diterpenoid possessing a 5/6/6/4 carbon ring system, together with eight known diterpenoids (2–9) were isolated from the stems of Jatropha podagrica. Their structures were elucidated by extensive spectroscopic methods and the absolute configuration of 1 was determined by single crystal X-ray diffraction analysis. All compounds were evaluated for their anti-inflammatory a ...
- DOI:
- 10.1016/S1875-5364(19)30033-0
- https://doi.org/10.1016/S1875-5364(19)30033-0
- Author:
- Xiu-Qing SONG; Jun-Sheng ZHANG; Shu-Juan YU; Jin-Hai YU; Hua ZHANG
- Source:
- Chinese journal of natural medicines 2019 v.17 no.4 pp. 303-307
- ISSN:
- 1875-5364
- Subject:
- Ipomoea nil; Oriental traditional medicine; acarbose; antioxidant activity; bioassays; enantiomers; enzyme inhibition; inhibitory concentration 50; seeds; spectral analysis
- Abstract:
- ... Four new octadecanoid derivatives (1–4) including a pair of enantiomers (1/2), along with 12 known analogues (5–16), were isolatedfrom the seeds of Ipomoea nil. Their structures were determined by detailed spectroscopic analyses and comparison with reported data of structurally related compounds, with the absolute configurations of 1 and 2 being assigned by an in situ dimolybdenum ECD method. Our ...
- DOI:
- 10.1016/S1875-5364(19)30034-2
- https://doi.org/10.1016/S1875-5364(19)30034-2
8. Rapid discovery and identification of the anti-inflammatory constituents in Zhi-Shi-Zhi-Zi-Chi-Tang
- Author:
- Hai-Qiang WANG; Yun-Xiang ZHU; Yi-Ning LIU; Ruo-Liu WANG; Shu-Fang WANG
- Source:
- Chinese journal of natural medicines 2019 v.17 no.4 pp. 308-320
- ISSN:
- 1875-5364
- Subject:
- Oriental traditional medicine; active ingredients; anti-inflammatory activity; flavones; liquid chromatography; mass spectrometry; nuclear magnetic resonance spectroscopy; prediction
- Abstract:
- ... The anti-inflammatory active ingredients of Zhi-Shi-Zhi-Zi-Chi-Tang (ZSZZCT), a traditional Chinese medicine formula, were predicted and identified using an approach based on activity index, LC-MS, semi-preparative LC and NMR. Firstly, the whole extract of ZSZZCT was analyzed using liquid chromatography-quadrupole time of flight-mass spectrometry (LC-Q-TOF-MS) and liquid chromatography - ion trap ...
- DOI:
- 10.1016/S1875-5364(19)30035-4
- https://doi.org/10.1016/S1875-5364(19)30035-4