Author: "Ji, Lin-Lin" / Journal: Chinese journal of natural medicines / Publication Year: 2019 / Subject: antineoplastic activity / Text Availability: Citation in PubAg

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Author:: JI, Lin-Lin, et al. ; LIN, Peng-Cheng; ZHONG, Xiang-Jian; LI, Jin-Jie; WANG, Xin; SHANG, Xiao-Ya; LIN, Sheng; Show all 7 Authors
Source:: Chinese journal of natural medicines 2019 v.17 no.1 pp. 22-26
ISSN:: 1875-5364
Subject:: Cirsium arvense; Oriental traditional medicine; animal ovaries; antineoplastic activity; cell lines; chemical structure; colorectal neoplasms; cytotoxicity; food plants; humans; inhibitory concentration 50; ovarian neoplasms; secretion; spectral analysis; triterpenoids; tumor necrosis factor-alpha
Abstract:: ... Guided by TNF-α secretion inhibitory activity assay, four taraxastane-type triterpenoids, including two new ones, 22-oxo-20-taraxasten-3β, 30-diol (1) and 22α-hydroxy-20-taraxasten-30β, 30-triol (2), have been obtained from an active fraction of the petroleum ether-soluble extract of the the medicinal and edible plant Cirsium setosum. Their structures were elucidated by spectroscopic data and CD d ...
DOI:: 10.1016/S1875-5364(19)30005-6
: https://dx.doi.org/10.1016/S1875-5364(19)30005-6