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- Oh, Seung Min; Kim, Ha Ryong; Park, Yong Joo; Lee, Yong Hwa; Chung, Kyu Hyuck
- Chinese journal of natural medicines 2015 v.13 no.11 pp. 808-814
- Oriental traditional medicine; Taraxacum mongolicum; breast neoplasms; cell proliferation; enzyme activity; estrogen receptors; estrogenic properties; estrogens; ethanol; gene expression; hormone replacement therapy; humans; in vitro studies; luciferase; messenger RNA; neoplasm cells; postmenopause; progesterone receptors; rats; reporter genes; reverse transcriptase polymerase chain reaction; tamoxifen; women
- ... Plants of the genus Taraxacum, commonly known as dandelions, are used to treat breast cancer in traditional folk medicine. However, their use has mainly been based on empirical findings without sufficient scientific evidence. Therefore, we hypothesized that dandelions would behave as a Selective estrogen receptor modulator (SERM) and be effective as hormone replacement therapy (HRT) in the postmen ...
- LV, Qi; ZHU, Xian-Yang; XIA, Yu-Feng; DAI, Yue; WEI, Zhi-Feng
- Chinese journal of natural medicines 2015 v.13 no.11 pp. 831-841
- Oriental traditional medicine; Stephania tetrandra; Western blotting; actin; cell lines; cell proliferation; guanosinetriphosphatase; mitogen-activated protein kinase; patients; phosphatidylinositol 3-kinase; protective effect; rats; rheumatoid arthritis; signal transduction
- ... Tetrandrine (Tet), the main active constituent of Stephania tetrandra root, has been demonstrated to alleviate adjuvant-induced arthritis in rats. The present study was designed to investigate the effects of Tet on the migration and invasion of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS) and explore the underlying mechanisms. By using cultures of primary FLS isolated from synoviums ...