Jump to Main Content
- Beauchemin, Mathieu; Morse, David
- Chromosoma 2018 v.127 no.1 pp. 29-43
- DNA replication; DNA-binding domains; Miozoa; RNA-binding proteins; cell cycle; chromosome morphology; eukaryotic cells; gene expression; histones; liquid crystals; mass spectrometry; messenger RNA; nucleosomes; organelles; proteomics; transcriptome
- ... Dinoflagellate chromatin is unique among eukaryotes, as the chromosomes are permanently condensed in a liquid crystal state instead of being packed in nucleosomes. However, how it is organized is still an unsolved mystery, in part due to the lack of a comprehensive catalog of dinoflagellate nuclear proteins. Here, we report the results of CHromatin Enrichment for Proteomics (CHEP) followed by shot ...
- Maksimov, DaniilA.; Laktionov, PetrP.; Posukh, OlgaV.; Belyakin, StepanN.; Koryakov, DmitryE.
- Chromosoma 2018 v.127 no.1 pp. 85-102
- Drosophila melanogaster; brain; epigenetics; eukaryotic cells; ganglia; gene silencing; genes; genome-wide association study; germ cells; heterochromatin; histones; males; methylation; mutation; salivary glands; somatic cells; spermatogenesis; testes; transcription (genetics)
- ... Histone modifications represent one of the key factors contributing to proper genome regulation. One of histone modifications involved in gene silencing is methylation of H3K9 residue. Present in the chromosomes across different eukaryotes, this epigenetic mark is controlled by SU(VAR)3-9 and its orthologs. Despite SU(VAR)3-9 was discovered over two decades ago, little is known about the details o ...