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- McNulty, Shannon M.; Sullivan, Beth A.
- Chromosome research 2018 v.26 no.3 pp. 115-138
- satellite DNA, etc ; epigenetics; genome; genome assembly; genomics; high-throughput nucleotide sequencing; humans; intergenic DNA; kinetochores; messenger RNA; non-coding RNA; proteins; satellite RNA; satellites; transcription (genetics); transcriptome; Show all 16 Subjects
- ... Repetitive DNA, formerly referred to by the misnomer “junk DNA,” comprises a majority of the human genome. One class of this DNA, alpha satellite, comprises up to 10% of the genome. Alpha satellite is enriched at all human centromere regions and is competent for de novo centromere assembly. Because of the highly repetitive nature of alpha satellite, it has been difficult to achieve genome assembli ...