Jump to Main Content
- Miga, Karen H.
- Chromosome research 2015 v.23 no.3 pp. 421-426
- satellite DNA, etc ; DNA assembly; chromosomes; evolution; genome; genomics; humans; models; tandem repeat sequences; Show all 9 Subjects
- ... Genomic studies rely on accurate chromosome assemblies to explore sequence-based models of cell biology, evolution and biomedical disease. However, even the extensively studied human genome has not yet reached a complete, ‘telomere-to-telomere’, chromosome assembly. The largest assembly gaps remain in centromeric regions and acrocentric short arms, sites known to contain megabase-sized arrays of t ...